Social circuits and their dysfunction in autism spectrum disorder
Social behaviors, how individuals act cooperatively and competitively with conspecifics, are
widely seen across species. Rodents display various social behaviors, and many different …
widely seen across species. Rodents display various social behaviors, and many different …
mTOR signaling disruption and its association with the development of autism spectrum disorder
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized
by impairments in social interaction and communication along with repetitive stereotypic …
by impairments in social interaction and communication along with repetitive stereotypic …
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus
Hydrocephalus, characterized by cerebral ventricular dilatation, is routinely attributed to
primary defects in cerebrospinal fluid (CSF) homeostasis. This fosters CSF shunting as the …
primary defects in cerebrospinal fluid (CSF) homeostasis. This fosters CSF shunting as the …
The choroid plexus: a missing link in our understanding of brain development and function
NR Saunders, KM Dziegielewska… - Physiological …, 2023 - journals.physiology.org
Studies of the choroid plexus lag behind those of the more widely known blood-brain barrier,
despite a much longer history. This review has two overall aims. The first is to outline long …
despite a much longer history. This review has two overall aims. The first is to outline long …
Three decades of valproate: a current model for studying autism Spectrum disorder
D Zarate-Lopez, AL Torres-Chávez… - Current …, 2024 - benthamdirect.com
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with increased
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …
prevalence and incidence in recent decades. Its etiology remains largely unclear, but it …
A neural stem cell paradigm of pediatric hydrocephalus
Pediatric hydrocephalus, the leading reason for brain surgery in children, is characterized by
enlargement of the cerebral ventricles classically attributed to cerebrospinal fluid (CSF) …
enlargement of the cerebral ventricles classically attributed to cerebrospinal fluid (CSF) …
The trilateral interactions between mammalian target of rapamycin (mTOR) signaling, the circadian clock, and psychiatric disorders: an emerging model
Abstract Circadian (~ 24 h) rhythms in physiology and behavior are evolutionarily conserved
and found in almost all living organisms. The rhythms are endogenously driven by daily …
and found in almost all living organisms. The rhythms are endogenously driven by daily …
[HTML][HTML] Rethinking the cilia hypothesis of hydrocephalus
PQ Duy, ABW Greenberg, WE Butler, KT Kahle - Neurobiology of Disease, 2022 - Elsevier
Dysfunction of motile cilia in ependymal cells has been proposed to be a pathogenic cause
of cerebrospinal fluid (CSF) overaccumulation leading to ventricular expansion in …
of cerebrospinal fluid (CSF) overaccumulation leading to ventricular expansion in …
Pathogenic variants in autism gene KATNAL2 cause hydrocephalus and disrupt neuronal connectivity by impairing ciliary microtubule dynamics
Enlargement of the cerebrospinal fluid (CSF)–filled brain ventricles (cerebral
ventriculomegaly), the cardinal feature of congenital hydrocephalus (CH), is increasingly …
ventriculomegaly), the cardinal feature of congenital hydrocephalus (CH), is increasingly …
Cholesterol regulation of membrane proteins revealed by two-color super-resolution imaging
Cholesterol and phosphatidyl inositol 4, 5-bisphosphate (PIP2) are hydrophobic molecules
that regulate protein function in the plasma membrane of all cells. In this review, we discuss …
that regulate protein function in the plasma membrane of all cells. In this review, we discuss …