An algorithmic immunohistochemical approach to define tumor type and assign site of origin

AM Bellizzi - Advances in anatomic pathology, 2020 - journals.lww.com
Immunohistochemistry represents an indispensable complement to an epidemiology and
morphology-driven approach to tumor diagnosis and site of origin assignment. This review …

[HTML][HTML] Clinicopathologic features of advanced squamous NSCLC

MA Socinski, C Obasaju, D Gandara, FR Hirsch… - Journal of Thoracic …, 2016 - Elsevier
Lung cancer remains the leading cause of cancer-related death worldwide. NSCLC
accounts for more than 85% of all lung cancers, and the prognosis for advanced-stage …

[HTML][HTML] p40 (ΔNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma

JA Bishop, J Teruya-Feldstein, WH Westra, G Pelosi… - Modern pathology, 2012 - Elsevier
Immunohistochemistry has recently emerged as a powerful ancillary tool for differentiating
lung adenocarcinoma and squamous cell carcinoma—a distinction with important …

p63 expression in human tumors and normal tissues: a tissue microarray study on 10,200 tumors

S Steurer, C Riemann, F Büscheck, AM Luebke… - Biomarker …, 2021 - Springer
Abstract Background Tumor protein 63 (p63) is a transcription factor of the p53 gene family
involved in differentiation of several tissues including squamous epithelium. p63 …

ALK-negative anaplastic large cell lymphoma: current concepts and molecular pathogenesis of a heterogeneous group of large T-cell lymphomas

S Pina-Oviedo, C Ortiz-Hidalgo, AA Carballo-Zarate… - Cancers, 2021 - mdpi.com
Simple Summary ALK-anaplastic large cell lymphoma (ALK-ALCL) is a rare subtype of
CD30+ large T-cell lymphoma that typically affects older adults and has a poor prognosis …

FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells

M van Keimpema, LJ Grüneberg… - Blood, The Journal …, 2014 - ashpublications.org
The forkhead transcription factor FOXP1 is involved in B-cell development and function and
is generally regarded as an oncogene in activated B-cell–like subtype of diffuse large B-cell …

Role of p63 in cancer development

V Graziano, V De Laurenzi - Biochimica et Biophysica Acta (BBA)-Reviews …, 2011 - Elsevier
Since their initial identification p53 homologues p63 and p73 have been expected to play a
role in cancer development due to their close homology to p53, notoriously one of the most …

The expression and clinical relevance of PD-1, PD-L1, and TP63 in patients with diffuse large B-cell lymphoma

X Fang, B Xiu, Z Yang, W Qiu, L Zhang, S Zhang, Y Wu… - Medicine, 2017 - journals.lww.com
Latest study showed that a novel translocation between programmed cell death ligand 1 (PD-
L1)(cluster of differentiation 274) and TP63 (tumor protein 63) can be found in diffuse large B …

Expression of p63 protein in anaplastic large cell lymphoma: implications for genetic subtyping

X Wang, RL Boddicker, S Dasari, JS Sidhu, ME Kadin… - Human pathology, 2017 - Elsevier
Anaplastic large cell lymphomas (ALCLs) are CD30-positive T-cell non-Hodgkin lymphomas
that bear chromosomal rearrangements of the TP53 homologue TP63 in a subset of cases …

Calretinin staining facilitates differentiation of olfactory neuroblastoma from other small round blue cell tumors in the sinonasal tract

JC Wooff, I Weinreb, B Perez-Ordonez… - The American journal …, 2011 - journals.lww.com
Objective: Olfactory neuroblastoma (ONB) is an uncommon malignant tumor of the sinonasal
tract and has a wide histologic differential diagnosis that includes other small round blue cell …