Metal–organic framework (MOF) materials are gaining significant interest in biomedical
research, owing to their high porosity, crystallinity, and structural and compositional diversity …

Over the past 3 years, the first bivalent protein degraders intentionally designed for targeted
protein degradation (TPD) have advanced to clinical trials, with an initial focus on …

Resveratrol is a well-studied dietary polyphenol with diverse health-promoting bioactivities.
However, the aqueous insolubility and chemical instability of resveratrol hamper its practical …

The freeze-thaw (F/T) method is commonly employed during the processing and handling of
drug substances to enhance their chemical and physical stability and obtain pharmaceutical …

Diazinon (DAZ) is an important organophosphorus pesticide, widely retained in the
environmental and food samples, badly affecting the ecological environment and human …

This review discusses the preparation of nanoparticles/nanosuspensions using wet milling
processes. It explores wet milling techniques, such as oscillatory bead milling, planetary …

Orally administered Sildenafil (SDF) is used to treat pulmonary arterial hypertension.
However, it has a relatively low bioavailability of approximately 40%. To circumvent such …

This study investigates the impact of charge and chain length of bile salts in the bilosomes
on the oral bioavailability of insulin (IN) by examining their uptake via the apical sodium …

Abstract Licochalcone-A (Lico-A) PLGA NPs functionalized with cell penetrating peptides B6
and Tet-1 are proposed for the treatment of ocular anti-inflammatory diseases. In this work …

Aim: The aim of this project is to use pectin-and chitosan-modified solid lipid nanoparticles
for bovine lactoferrin to enhance its cellular uptake and transport. Methods: Solid lipid …