Childhood adversity and neural development: A systematic review

KA McLaughlin, D Weissman… - Annual review of …, 2019 - annualreviews.org
An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

Toward a formal theory for computing machines made out of whatever physics offers

H Jaeger, B Noheda, WG Van Der Wiel - Nature communications, 2023 - nature.com
Approaching limitations of digital computing technologies have spurred research in
neuromorphic and other unconventional approaches to computing. Here we argue that if we …

Representational drift: Emerging theories for continual learning and experimental future directions

LN Driscoll, L Duncker, CD Harvey - Current Opinion in Neurobiology, 2022 - Elsevier
Recent work has revealed that the neural activity patterns correlated with sensation,
cognition, and action often are not stable and instead undergo large scale changes over …

Targeted neurotechnology restores walking in humans with spinal cord injury

FB Wagner, JB Mignardot, CG Le Goff-Mignardot… - Nature, 2018 - nature.com
Spinal cord injury leads to severe locomotor deficits or even complete leg paralysis. Here we
introduce targeted spinal cord stimulation neurotechnologies that enabled voluntary control …

Activity-regulated transcription: bridging the gap between neural activity and behavior

EL Yap, ME Greenberg - Neuron, 2018 - cell.com
Gene transcription is the process by which the genetic codes of organisms are read and
interpreted as a set of instructions for cells to divide, differentiate, migrate, and mature. As …

Spinal cord repair: advances in biology and technology

G Courtine, MV Sofroniew - Nature medicine, 2019 - nature.com
Individuals with spinal cord injury (SCI) can face decades with permanent disabilities.
Advances in clinical management have decreased morbidity and improved outcomes, but …

Structure and function of a neocortical synapse

S Holler, G Köstinger, KAC Martin, GFP Schuhknecht… - Nature, 2021 - nature.com
In 1986, electron microscopy was used to reconstruct by hand the entire nervous system of a
roundworm, the nematode Caenorhabditis elegans. Since this landmark study, high …

Hallucinogens in mental health: preclinical and clinical studies on LSD, psilocybin, MDMA, and ketamine

D De Gregorio, A Aguilar-Valles, KH Preller… - Journal of …, 2021 - Soc Neuroscience
A revamped interest in the study of hallucinogens has recently emerged, especially with
regard to their potential application in the treatment of psychiatric disorders. In the last …

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

RS Duman, GK Aghajanian, G Sanacora, JH Krystal - Nature medicine, 2016 - nature.com
Depression is a common, devastating illness. Current pharmacotherapies help many
patients, but high rates of a partial response or no response, and the delayed onset of the …

Microglia contact induces synapse formation in developing somatosensory cortex

A Miyamoto, H Wake, AW Ishikawa, K Eto… - Nature …, 2016 - nature.com
Microglia are the immune cells of the central nervous system that play important roles in
brain pathologies. Microglia also help shape neuronal circuits during development, via …