Is enzyme immobilization a mature discipline? Some critical considerations to capitalize on the benefits of immobilization

JM Bolivar, JM Woodley… - Chemical Society …, 2022 - pubs.rsc.org
Enzyme immobilization has been developing since the 1960s and although many industrial
biocatalytic processes use the technology to improve enzyme performance, still today we …

The molecular processes of urea hydrolysis in relation to ammonia emissions from agriculture

JJ Sigurdarson, S Svane, H Karring - Reviews in Environmental Science …, 2018 - Springer
Ammonia emissions from the agricultural sector give rise to numerous environmental and
societal concerns and represent an economic challenge in crop farming, causing a loss of …

The structure-based reaction mechanism of urease, a nickel dependent enzyme: tale of a long debate

L Mazzei, F Musiani, S Ciurli - JBIC Journal of Biological Inorganic …, 2020 - Springer
This review is an attempt to retrace the chronicle that starts from the discovery of the role of
nickel as the essential metal ion in urease for the enzymatic catalysis of urea, a key step in …

[HTML][HTML] Recent advances in design of new urease inhibitors: A review

P Kafarski, M Talma - Journal of advanced research, 2018 - Elsevier
Urease is a nickel-dependent metalloenzyme found in plants, some bacteria, and fungi.
Bacterial enzyme is of special importance since it has been demonstrated as a potent …

Urease and nitrification inhibitors—As mitigation tools for greenhouse gas emissions in sustainable dairy systems: A review

MP Byrne, JT Tobin, PJ Forrestal, M Danaher… - Sustainability, 2020 - mdpi.com
Currently, nitrogen fertilizers are utilized to meet 48% of the total global food demand. The
demand for nitrogen fertilizers is expected to grow as global populations continue to rise …

Inhibition of urease activity by different compounds provides insight into the modulation and association of bacterial nickel import and ureolysis

S Svane, JJ Sigurdarson, F Finkenwirth, T Eitinger… - Scientific reports, 2020 - nature.com
The nickel-dependent urease enzyme is responsible for the hydrolysis of urea to ammonia
and carbon dioxide. A number of bacteria produce urease (ureolytic bacteria) and are …

The structure of the elusive urease–urea complex unveils the mechanism of a paradigmatic nickel‐dependent enzyme

L Mazzei, M Cianci, S Benini… - Angewandte Chemie …, 2019 - Wiley Online Library
Urease, the most efficient enzyme known, contains an essential dinuclear NiII cluster in the
active site. It catalyzes the hydrolysis of urea, inducing a rapid pH increase that has negative …

Effect of pyroligneous acid on soil urease, amidase, and nitrogen use efficiency by Chinese cabbage (Brassica campestris var. Pekinensis)

JK Lee, HJ Park, SJ Cha, SJ Kwon, JH Park - Environmental Pollution, 2021 - Elsevier
Urea is one of the most commonly used nitrogen fertilizers in agricultural soil and is easily
decomposed by soil urease resulting in ammonium release. The produced ammonium can …

Synthesis and biological activities of drugs for the treatment of osteoporosis

S Zhou, G Huang, G Chen - European journal of medicinal chemistry, 2020 - Elsevier
Osteoporosis is an asymptomatic progressive disease. With the improvement of people's
living standard and the aging of population, osteoporosis and its fracture have become one …

The structure of urease inactivated by Ag (I): a new paradigm for enzyme inhibition by heavy metals

L Mazzei, M Cianci, AG Vara, S Ciurli - Dalton transactions, 2018 - pubs.rsc.org
The nickel-dependent enzyme urease is a virulence factor for a large number of human
pathogens, as well as a negative element for the efficiency of soil nitrogen fertilization for …