[HTML][HTML] Filopodia in cell adhesion, 3D migration and cancer cell invasion

G Jacquemet, H Hamidi, J Ivaska - Current opinion in cell biology, 2015 - Elsevier
This review discusses recent advances in our understanding of the role filopodia and
filopodia-like structures in cell adhesion and three dimensional (3D) cell migration both in …

Optical forces: from fundamental to biological applications

H Xin, Y Li, YC Liu, Y Zhang, YF Xiao… - Advanced Materials, 2020 - Wiley Online Library
Optical forces, generally arising from changes of field gradients or linear momentum carried
by photons, form the basis for optical trapping and manipulation. Advances in optical forces …

[HTML][HTML] Cell protrusions and contractions generate long-range membrane tension propagation

H De Belly, S Yan, HB da Rocha, S Ichbiah, JP Town… - Cell, 2023 - cell.com
Membrane tension is thought to be a long-range integrator of cell physiology. Membrane
tension has been proposed to enable cell polarity during migration through front-back …

Filopodia in vitro and in vivo

TCA Blake, JL Gallop - Annual Review of Cell and …, 2023 - annualreviews.org
Filopodia are dynamic cell surface protrusions used for cell motility, pathogen infection, and
tissue development. The molecular mechanisms determining how and where filopodia grow …

Mechanisms shaping cell membranes

MM Kozlov, F Campelo, N Liska… - Current opinion in cell …, 2014 - Elsevier
Membranes of intracellular organelles are characterized by large curvatures with radii of the
order of 10–30 nm. While, generally, membrane curvature can be a consequence of any …

Stress relaxation, dynamics, and plasticity of transient polymer networks

F Meng, RH Pritchard, EM Terentjev - Macromolecules, 2016 - ACS Publications
We propose a theoretical framework for dealing with a transient polymer network
undergoing small deformations, based on the rate of breaking and reforming of network …

Filopodia and their links with membrane traffic and cell adhesion

JL Gallop - Seminars in cell & developmental biology, 2020 - Elsevier
Filopodia are dynamic, narrow, plasma membrane protrusions filled with bundled actin
filaments. Fresh actin monomers are incorporated at the tips furthest away from the cell …

Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration

MC Kim, YR Silberberg, R Abeyaratne… - Proceedings of the …, 2018 - National Acad Sciences
Filopodia have a key role in sensing both chemical and mechanical cues in surrounding
extracellular matrix (ECM). However, quantitative understanding is still missing in the …

MYO10-filopodia support basement membranes at pre-invasive tumor boundaries

E Peuhu, G Jacquemet, CLGJ Scheele, A Isomursu… - Developmental Cell, 2022 - cell.com
Ductal carcinoma in situ (DCIS) is a pre-invasive stage of breast cancer. During invasion, the
encapsulating DCIS basement membrane (BM) is compromised, and tumor cells invade the …

Activated I-BAR IRSp53 clustering controls the formation of VASP-actin–based membrane protrusions

FC Tsai, JM Henderson, Z Jarin, E Kremneva… - Science …, 2022 - science.org
Filopodia are actin-rich membrane protrusions essential for cell morphogenesis, motility,
and cancer invasion. How cells control filopodium initiation on the plasma membrane …