Protein–polyelectrolyte interactions

AB Kayitmazer, D Seeman, BB Minsky, PL Dubin, Y Xu - Soft Matter, 2013 - pubs.rsc.org
The interactions of proteins and polyelectrolytes lead to diverse applications in separations,
delivery and wound repair, and are thus of interest to scientists in eg (a) glycobiology,(b) …

Protein folding, misfolding, and aggregation. Formation of inclusion bodies and aggresomes

KA Markossian, BI Kurganov - Biochemistry (Moscow), 2004 - Springer
In this review the mechanisms of protein folding, misfolding, and aggregation as well as the
mechanisms of cell defense against toxic protein aggregates are considered. Misfolded and …

A Lumry− Eyring nucleated polymerization model of protein aggregation kinetics: 1. Aggregation with pre-equilibrated unfolding

JM Andrews, CJ Roberts - The Journal of Physical Chemistry B, 2007 - ACS Publications
A mathematical model is presented of the kinetics of non-native protein aggregation that
combines Lumry− Eyring and nucleated polymerization (LENP) descriptions. The LENP …

Thermostable red and green light-producing firefly luciferase mutants for bioluminescent reporter applications

BR Branchini, DM Ablamsky, MH Murtiashaw… - Analytical …, 2007 - Elsevier
Light emission from the North American firefly Photinus pyralis, which emits yellow–green
(557-nm) light, is widely believed to be the most efficient bioluminescence system known …

Grp94 works upstream of BiP in protein remodeling under heat stress

YS Amankwah, P Collins, Y Fleifil, E Unruh… - Journal of Molecular …, 2022 - Elsevier
Hsp90 and Hsp70 are highly conserved molecular chaperones that promote the proper
folding and activation of substrate proteins that are often referred to as clients. The two …

Multimerization and aggregation of native-state insulin: effect of zinc

Y Xu, Y Yan, D Seeman, L Sun, PL Dubin - Langmuir, 2012 - ACS Publications
The aggregation of insulin is complicated by the coexistence of various multimers, especially
in the presence of Zn2+. Most investigations of insulin multimerization tend to overlook …

Arginine ethylester prevents thermal inactivation and aggregation of lysozyme

K Shiraki, M Kudou, S Nishikori… - European journal of …, 2004 - Wiley Online Library
Arginine is a versatile additive to prevent protein aggregation. This paper shows that
arginine ethylester (ArgEE) prevents heat‐induced inactivation and aggregation of hen egg …

A change in the aggregation pathway of bovine serum albumin in the presence of arginine and its derivatives

VA Borzova, KA Markossian, SY Kleymenov… - Scientific reports, 2017 - nature.com
Chemical chaperones including arginine and its derivatives are widely used by biochemists
working on the design of agents, which are able to efficiently suppress protein aggregation …

Refolding Increases the Chaperone-like Activity of αH-Crystallin and Reduces Its Hydrodynamic Diameter to That of α-Crystallin

KO Muranov, NB Poliansky, VA Borzova… - International Journal of …, 2023 - mdpi.com
αH-Crystallin, a high molecular weight form of α-crystallin, is one of the major proteins in the
lens nucleus. This high molecular weight aggregate (HMWA) plays an important role in the …

Mechanism of co-aggregation in a protein mixture with small additives

S Oki, K Iwashita, M Kimura, H Kano… - International journal of …, 2018 - Elsevier
Co-aggregation plays an important role in processing protein-rich food materials under
heterogeneous conditions. The main cause of co-aggregation is an electrostatic attraction …