Mobile oxazolidinone resistance genes in Gram-positive and Gram-negative bacteria

S Schwarz, W Zhang, XD Du, H Krüger… - Clinical microbiology …, 2021 - Am Soc Microbiol
Seven mobile oxazolidinone resistance genes, including cfr, cfr (B), cfr (C), cfr (D), cfr (E),
optrA, and poxtA, have been identified to date. The cfr genes code for 23S rRNA methylases …

Regulation of resistance in vancomycin-resistant enterococci: the VanRS two-component system

AA Guffey, PJ Loll - Microorganisms, 2021 - mdpi.com
Vancomycin-resistant enterococci (VRE) are a serious threat to human health, with few
treatment options being available. New therapeutics are urgently needed to relieve the …

Dissemination of Enterococcal genetic lineages: a one health perspective

J Monteiro Marques, M Coelho, AR Santana, D Pinto… - Antibiotics, 2023 - mdpi.com
Enterococcus spp. are commensals of the gastrointestinal tracts of humans and animals and
colonize a variety of niches such as water, soil, and food. Over the last three decades …

Genomic insights into linezolid-resistant Enterococci revealed its evolutionary diversity and poxtA copy number heterogeneity

Q Wang, K Peng, Z Liu, Y Li, X Xiao, XD Du, R Li… - International Journal of …, 2023 - Elsevier
Objectives This study aimed to determine the molecular mechanisms of linezolid-resistant
enterococci (LRE) in swine slaughterhouses in China and apply the “One Health” …

Antimicrobial use in Brazilian swine herds: assessment of use and reduction examples

MC Dutra, LZ Moreno, RA Dias, AM Moreno - Microorganisms, 2021 - mdpi.com
Brazil, as a major pig producer, is currently experiencing the widespread use of
antimicrobials as a serious issue to be addressed. For measures to be taken in this direction …

Enterococci as a One Health indicator of antimicrobial resistance

SZ Zaidi, R Zaheer, A Zovoilis… - Canadian Journal of …, 2024 - cdnsciencepub.com
The rapid increase of antimicrobial-resistant bacteria in humans and livestock is concerning.
Antimicrobials are essential for the treatment of disease in modern day medicine, and their …

Genetic characterization of MDR genomic elements carrying two aac(6′)-aph(2″) genes in feline-derived clinical Enterococcus faecalis isolate

XS Li, Y Qi, P Li, J Xue, X Li, I Muhammad, Y Li… - Frontiers in …, 2023 - frontiersin.org
Multidrug-resistant Enterococcus faecalis (E. faecalis) often cause intestinal infections in
cats. The aim of this study was to investigate a multidrug-resistant E. faecalis isolate for …

Molecular epidemiology, phenotypic and genomic characterization of antibiotic-resistant enterococcal isolates from diverse farm animals in Xinjiang, China

W Chen, Q Wang, H Wu, P Xia, R Tian, R Li… - Science of The Total …, 2024 - Elsevier
Multidrug-resistant (MDR) bacteria in farm environments can be transferred to humans
through the food chain and occupational exposure. Enterococcus infections caused by …

First report of the optrA-carrying multidrug resistance genomic island in Campylobacter jejuni isolated from pigeon meat

S Tang, R Yang, Q Wu, Y Ding, Z Wang, J Zhang… - International Journal of …, 2021 - Elsevier
Campylobacter spp., such as Campylobacter jejuni and Campylobacter coli, are important
zoonotic Gram-negative pathogens that cause acute intestinal diseases in humans. The …

Coexistence of the Oxazolidinone Resistance–Associated Genes cfr and optrA in Enterococcus faecalis From a Healthy Piglet in Brazil

LM Almeida, A Gaca, PM Bispo, F Lebreton… - Frontiers in public …, 2020 - frontiersin.org
Oxazolidinones are one of the most important antimicrobials potentially active against
glycopeptide-and β-lactam-resistant Gram-positive pathogens. Linezolid—the first …