Introduction: Rhodanines, as one of the 4-thiazolidinones subtypes, are recognized as
privileged heterocycles in medicinal chemistry. The main achievements include the …

Thiazolidin-4-one scaffold has great potential for medicinal chemistry and is of interest to
scientists in view of wide spectrum of biological activity. This scaffold is often used for …

The ever-increasing incidence of drug-resistant Mycobacterium tuberculosis infections has
invigorated the focus on the discovery and development of novel treatment options. The …

This work aims at elucidating the mechanism and kinetics of hydrolysis of GANT61, the first
and most-widely used inhibitor of the Hedgehog (Hh) signalling pathway that targets Glioma …

In search of new active molecules against Mycobacterium tuberculosis (MTB) H37Ra and
Mycobacterium bovis BCG, a small focused library of rhodanine incorporated …

A series of rhodanine incorporated quinoline derivatives were efficiently synthesized using
reusable DBU acetate as ionic liquid and evaluated for their in vitro antitubercular activity …

Having demonstrated previously that deletion of zinc metalloprotease zmp1 in
Mycobacterium bovis BCG increased immunogenicity of BCG vaccines, we here …

The enzyme Zmp1 is a zinc‐containing peptidase that plays a critical role in the
pathogenicity of Mycobacterium tuberculosis. Herein we describe the identification of a small …

Mycobacterium tuberculosis is the causative agent of tuberculosis, an ancient disease
which, still today, represents a major threat for the world population. Despite the advances in …

We have described a highly efficient, safer protocol for the synthesis of 5-arylidene-
rhodanine conjugates catalyzed by Bronsted acidic ionic liquid [Et 3 NH][HSO 4] in excellent …