An ultrasound-exclusive non-invasive computational diagnostic framework for personalized cardiology of aortic valve stenosis

N Bahadormanesh, B Tomka, M Kadem… - Medical Image …, 2023 - Elsevier
Aortic stenosis (AS) is an acute and chronic cardiovascular disease and If left untreated,
50% of these patients will die within two years of developing symptoms. AS is characterized …

Reducing long‐term mortality post transcatheter aortic valve replacement requires systemic differentiation of patient‐specific coronary hemodynamics

S Khodaei, L Garber, M Abdelkhalek… - Journal of the …, 2023 - Am Heart Assoc
Background Despite the proven benefits of transcatheter aortic valve replacement (TAVR)
and its recent expansion toward the whole risk spectrum, coronary artery disease is present …

Long-term prognostic impact of paravalvular leakage on coronary artery disease requires patient-specific quantification of hemodynamics

S Khodaei, L Garber, J Bauer, A Emadi… - Scientific Reports, 2022 - nature.com
Transcatheter aortic valve replacement (TAVR) is a frequently used minimally invasive
intervention for patient with aortic stenosis across a broad risk spectrum. While coronary …

Impact of TAVR on coronary artery hemodynamics using clinical measurements and image‐based patient‐specific in silico modeling

L Garber, S Khodaei, N Maftoon… - Scientific Reports, 2023 - nature.com
In recent years, transcatheter aortic valve replacement (TAVR) has become the leading
method for treating aortic stenosis. While the procedure has improved dramatically in the …

[HTML][HTML] Early detection of risk of neo-sinus blood stasis post-transcatheter aortic valve replacement using personalized hemodynamic analysis

S Khodaei, M Abdelkhalek, N Maftoon, A Emadi… - Structural Heart, 2023 - Elsevier
Background Despite the demonstrated benefits of transcatheter aortic valve replacement
(TAVR), subclinical leaflet thrombosis and hypoattenuated leaflet thickening are commonly …

A Doppler-exclusive non-invasive computational diagnostic framework for personalized transcatheter aortic valve replacement

N Bahadormanesh, B Tomka, M Abdelkhalek… - Scientific Reports, 2023 - nature.com
Given the associated risks with transcatheter aortic valve replacement (TAVR), it is crucial to
determine how the implant will affect the valve dynamics and cardiac function, and if TAVR …

A temporal fluid-parcel backwards-tracing method for Direct-Numerical and Large-Eddy Simulation employing Lagrangian particles

L Engelmann, C Welch, M Schmidt, D Meller, P Wollny… - Applied Energy, 2023 - Elsevier
In this study, a method which allows for causal backtracing of turbulent flow phenomena is
suggested. Key events in technical processes based on turbulent mixing can thereby be …

Repaired Tetralogy of Fallot pressure assessment: insights from 4D-flow pressure mapping

S Ihsan Ali, D Patton, KA Myers, J Garcia - Fluids, 2023 - mdpi.com
Tetralogy of Fallot (TOF) is the most prevalent cyanotic congenital heart defect (CHD) that
alters normal blood flow through the heart and accounts for 10% of all CHD. Pulmonary …

Stress Load and Ascending Aortic Aneurysms: An Observational, Longitudinal, Single-Center Study Using Computational Fluid Dynamics

FS de Azevedo, GC Almeida, B Alvares de Azevedo… - Bioengineering, 2024 - mdpi.com
Ascending aortic aneurysm (AAoA) is a silent disease with high mortality; however, the
factors associated with a worse prognosis are not completely understood. The objective of …

A multi-domain lattice Boltzmann mesh refinement method for non-Newtonian blood flow modeling

MA Daeian, WS Smith, Z Keshavarz-Motamed - Physics of Fluids, 2025 - pubs.aip.org
a) Authors to whom correspondence should be addressed:[email protected]. URL:
https://www. eng. mcmaster. ca/cas/faculty/dr-spencer-smith/; https://www. cas. mcmaster …