Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Electrochemical biosensors for whole blood analysis: recent progress, challenges, and future perspectives

S Li, H Zhang, M Zhu, Z Kuang, X Li, F Xu… - Chemical …, 2023 - ACS Publications
Whole blood, as one of the most significant biological fluids, provides critical information for
health management and disease monitoring. Over the past 10 years, advances in …

[HTML][HTML] Applied machine learning as a driver for polymeric biomaterials design

SM McDonald, EK Augustine, Q Lanners… - Nature …, 2023 - nature.com
Polymers are ubiquitous to almost every aspect of modern society and their use in medical
products is similarly pervasive. Despite this, the diversity in commercial polymers used in …

The living interface between synthetic biology and biomaterial design

AP Liu, EA Appel, PD Ashby, BM Baker, E Franco… - Nature materials, 2022 - nature.com
Recent far-reaching advances in synthetic biology have yielded exciting tools for the
creation of new materials. Conversely, advances in the fundamental understanding of soft …

[HTML][HTML] Mucosa-interfacing electronics

K Nan, VR Feig, B Ying, JG Howarth, Z Kang… - Nature Reviews …, 2022 - nature.com
The surface mucosa that lines many of our organs houses myriad biometric signals and,
therefore, has great potential as a sensor–tissue interface for high-fidelity and long-term …

Implantable hydrogel-protective DNA aptamer-based sensor supports accurate, continuous electrochemical analysis of drugs at multiple sites in living rats

S Li, J Dai, M Zhu, N Arroyo-Currás, H Li, Y Wang… - ACS …, 2023 - ACS Publications
The ability to track the levels of specific molecules, such as drugs, metabolites, and
biomarkers, in the living body, in real time and for long durations, would improve our …

[HTML][HTML] Biomolecular sensors for advanced physiological monitoring

CD Flynn, D Chang, A Mahmud, H Yousefi… - Nature Reviews …, 2023 - nature.com
Body-based biomolecular sensing systems, including wearable, implantable and
consumable sensors allow comprehensive health-related monitoring. Glucose sensors have …

Machine-Learning-Guided Discovery of 19F MRI Agents Enabled by Automated Copolymer Synthesis

M Reis, F Gusev, NG Taylor, SH Chung… - Journal of the …, 2021 - ACS Publications
Modern polymer science suffers from the curse of multidimensionality. The large chemical
space imposed by including combinations of monomers into a statistical copolymer …

An antibody-based molecular switch for continuous small-molecule biosensing

IAP Thompson, J Saunders, L Zheng, AA Hariri… - Science …, 2023 - science.org
We present a generalizable approach for designing biosensors that can continuously detect
small-molecule biomarkers in real time and without sample preparation. This is achieved by …

A wearable electrochemical sensor based on anti-fouling and self-healing polypeptide complex hydrogels for sweat monitoring

X Qiao, Y Cai, Z Kong, Z Xu, X Luo - ACS sensors, 2023 - ACS Publications
Although continuous monitoring of constituents in complex sweat is crucial for noninvasive
physiological evaluation, biofouling on the sweat sensor surface and inadequate flexible self …