Various antibiotics have been used in the treatment of cancers, via their anti-proliferative,
pro-apoptotic and anti-epithelial-mesenchymal-transition (EMT) capabilities. However …

Solid-state fermentation is an alternative culture method that has gained researchers
attention over the past 20 years. There are several advantages in employing many SSF …

Statins are a group of extremely successful drugs that lower cholesterol levels in blood;
decreasing the risk of heath attack or stroke. In recent years, statins have also been reported …

Lovastatin, and its semisynthetic derivative simvastatine, has great medical and economic
importance, besides great potential for other uses. In the last years, a deeper and more …

A novel solid-state fermentation (SSF) process, using high-density polyurethane foam (PUF)
as an inert support, was developed for the production of lovastatin. Results indicated that …

Molecular studies were performed to establish the causes of the superior lovastatin
productivity of a novel solid-state fermentation (SSF) process, in relation with liquid …

Pd (II) complex was prepared from the interaction with Schiff base based on the
condensation amoxicillin trihydrate drug and 4‐N, N‐dimethylaminobenzaldehyde. The …

The knowledge on the regulation of secondary metabolites (SMs) has traditionally been
important for the design of culture media, for process control strategies, and reactor design …

Gemcitabine is a nucleoside analog widely used as an anticancer agent against several
types of cancer. Although gemcitabine sometimes shows excellent effectiveness, cancer …

The rapid emergence of antimicrobial resistance among pathogens has led to a renewed
interest to search for novel antimicrobial agents. The history of new drug discovery …