The use of the intoxicating cannabinoid delta‐8‐tetrahydrocannabinol (Δ8‐THC) has grown
rapidly over the last several years. There have been dozens of Δ8‐THC studies dating back …

Post‐transcriptional gene silencing targets and degrades mRNA transcripts, silencing the
expression of specific genes. RNA interference technology, using synthetic structurally well …

Pituitary neuroendocrine tumors (PitNETs) are common, with five main histological subtypes:
lactotroph, somatotroph, and thyrotroph (POU1F1/PIT1 lineage); corticotroph (TBX19/TPIT …

G protein–coupled receptors are the largest and pharmacologically most important receptor
family and are involved in the regulation of most cell functions. Most of them reside …

Background and Purpose Short‐chain fatty acids (SCFAs) are metabolites from gut microbes
involved in the host's inflammatory response and immunity. The aim of this study was to …

The pineal hormone melatonin has attracted great scientific interest since its discovery in
1958. Despite the enormous number of basic and clinical studies the exact role of melatonin …

Major depressive disorder is a leading cause of disability worldwide. Because conventional
therapies are ineffective in many patients, novel strategies are needed to overcome …

Das macht das Buch aus: Der „Silbernagel “, wie viele dieses Buch nennen, zeichnet sich
durch die grobe Unterteilung in die zahlreichen klar strukturierten Kapitel aus, die häufig …

Background and Purpose Muscle protein catabolism in patients with diabetic nephropathy
(DN) results in striking loss of muscle proteins, which increases morbidity and mortality risks …

Background and Purpose Mitochondrial damage and oxidative stress are crucial
contributors to the tubular cell injury and death in acute kidney injury. Novel therapeutic …