The role of long non-coding RNA H19 in infertility

Y Peng, R Guo, B Shi, D Li - Cell Death Discovery, 2023 - nature.com
Infertility is defined as the failure to conceive after at least one year of unprotected
intercourse. Long non-coding RNAs (lncRNAs) are transcripts that contain more than 200 …

A view on uterine leiomyoma genesis through the prism of genetic, epigenetic and cellular heterogeneity

AS Koltsova, OA Efimova, AA Pendina - International Journal of …, 2023 - mdpi.com
Uterine leiomyomas (ULs), frequent benign tumours of the female reproductive tract, are
associated with a range of symptoms and significant morbidity. Despite extensive research …

[HTML][HTML] Genome-wide association analysis and pathways enrichment for lactation persistency in Canadian Holstein cattle

DN Do, N Bissonnette, P Lacasse, F Miglior… - Journal of Dairy …, 2017 - Elsevier
Lactation persistency (LP), defined as the rate of declining milk yield after milk peak, is an
economically important trait for dairy cattle. Improving LP is considered a good alternative …

H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas

T Cao, Y Jiang, Z Wang, N Zhang, A Al-Hendy… - Oncogene, 2019 - nature.com
Uterine leiomyomas or fibroids (UFs) are benign tumors characterized by hyperplastic
smooth muscle cells and excessive deposition of extracellular matrix (ECM). Afflicting~ 80 …

A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids

TL Edwards, A Giri, JN Hellwege, KE Hartmann… - Frontiers in …, 2019 - frontiersin.org
Uterine fibroids affect up to 77% of women by menopause and account for up to $34 billion
in healthcare costs each year. Although fibroid risk is heritable, genetic risk for fibroids is not …

A multi-stage genome-wide association study of uterine fibroids in African Americans

JN Hellwege, JM Jeff, LA Wise, CS Gallagher… - Human genetics, 2017 - Springer
Uterine fibroids are benign tumors of the uterus affecting up to 77% of women by
menopause. They are the leading indication for hysterectomy, and account for $34 billion …

The effect of race/ethnicity and MED12 mutation on the expression of long non-coding RNAs in uterine leiomyoma and myometrium

TD Chuang, N Ton, S Rysling, D Boos… - International journal of …, 2024 - mdpi.com
The objective of this study was to elucidate the expression of long non-coding RNA
(lncRNA) in leiomyomas (Lyo) and paired myometrium (Myo) and explore the impact of race …

GRAF2, WDR44, and MICAL1 mediate Rab8/10/11–dependent export of E-cadherin, MMP14, and CFTR ΔF508

S Lucken-Ardjomande Häsler, Y Vallis… - Journal of Cell …, 2020 - rupress.org
In addition to the classical pathway of secretion, some transmembrane proteins reach the
plasma membrane through alternative routes. Several proteins transit through endosomes …

Admixture mapping of genetic variants for uterine fibroids

K Zhang, H Wiener, B Aissani - Journal of human genetics, 2015 - nature.com
Uterine leiomyoma (UL) are benign neoplasms arising from the smooth muscle cells of the
uterus. One of the established risk factors for UL is African American ethnicity. Studies have …

[HTML][HTML] α-1, 2-Mannosidase MAN1C1 inhibits proliferation and invasion of clear cell renal cell carcinoma

H Li, G Wang, Y Yu, W Jian, D Zhang, Y Wang… - Journal of …, 2018 - ncbi.nlm.nih.gov
Background: This study investigated the biological function of the gene MAN1C1 α-
mannosidase in renal cell carcinoma. It has been reported that MAN1C1 is probably a …