Abstract Poly (α-l-lysine)(PLL) is a class of water-soluble, cationic biopolymer composed of α-
l-lysine structural units. The previous decade witnessed tremendous progress in the …

In recent decades, peptides, which can possess high potency, excellent selectivity, and low
toxicity, have emerged as promising therapeutics for cancer applications. Combined with an …

It remains a conundrum to reconcile the contradiction between effective tumor retention and
deep intratumor infiltration for nanotherapeutics due to the sophisticated drug delivery …

The past decades witnessed an increasing interest in peptides as clinical therapeutics.
Rightfully considered as a potential alternative for small molecule therapy, these remarkable …

Purpose This study aimed to fabricate tumor-originated extracellular vesicles (EVs) targeting
tumors for use in combination with immunotherapy and chemotherapy. Methods The …

Combination therapy has become an effective strategy for tumor treatment, but the
preparation of drug nanocarriers with the high requirements still lacked exploration. In this …

To optimize the therapeutic efficacy of active pharmaceutical ingredients, various lipid-based
drug delivery systems have been developed. In particular, due to the various advantages …

Atopic dermatitis is a chronic inflammatory skin condition that is characterized by skin
inflammation, itching, and redness. Although various treatments can alleviate symptoms …

To combat the ever-growing increase of multidrug-resistant (MDR) bacteria, action must be
taken in the development of antibiotic formulations. Colistin, an effective antibiotic, was …

Cancer is the result of disturbed cell functions. Cancer is induced by the accumulation of
many genetic and epigenetic changes within the cell, expressed in the accumulation of …