The applications of fluorinated molecules in bioengineering and nanotechnology are
expanding rapidly with the controlled introduction of fluorine being broadly studied due to …

Fluoropolymers have unique physicochemical properties such as hydrophobicity and
lipophobicity, good chemical stability and bio-inertness, low surface energy and phase …

The design of efficient and universal carriers to transport proteins into cells is highly
desirable in the development of biotherapeutics. However, intracellular protein delivery …

Research into the application of nanocarriers in the delivery of cancer-fighting drugs has
been a promising research area for decades. On the other hand, their cytotoxic effects on …

Dendrimers are nano-sized and three-dimensional macromolecules with well-defined
globular architecture and are widely used in various aspects such as drug and gene delivery …

Polyethyleneimine (PEI) has been extensively investigated as an efficient carrier for nucleic
acid delivery. Yet, it suffers from a high toxicity profile that hinders clinical translation …

Tremendous efforts have been made to improve polymeric property in gene delivery
performances, especially when obstacle of transferring gene construct into difficult-to …

RNA interference with the ability to specifically silence target genes has shown great
potential to treat various diseases. The primary challenge for RNA interference is to …

Incorporation of fluorinated moieties in polymeric nanoparticles has been shown in many
instances to increase their uptake by living cells and, hence, has proven to be a useful …

Metastatic breast cancer is a major cause of cancer-related female mortality worldwide. The
signal transducer and activator of transcription 3 (STAT3) and the chemokine receptor …