Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by erosive
polyarthritis. Beyond joint pathology, RA is associated with neuropsychiatric comorbidity …

Depression is a common and disabling comorbidity in rheumatoid arthritis that not only
decreases the likelihood of remission and treatment adherence but also increases the risk of …

Microglia is a heterogeneous population that mediates neuroinflammation in the central
nervous system (CNS) and plays a crucial role in developing neuropathic pain. FKBP5 …

Chronic inflammatory pain (CIP) is a common public medical problem, often accompanied
by memory impairment. However, the mechanisms underlying CIP and comorbid memory …

Abstract Background Traditional Chinese medicine (TCM) prescriptions have multiple
bioactive properties.“Gui Zhi–Shao Yao” herb pair is widely used to treat chronic pain (CP) …

Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic inflammation
and the destruction of joints and systemic organs. RA is commonly accompanied by …

Depression and anxiety commonly occur in chronic pain states and the coexistence of these
diseases worsens outcomes for both disorders and may reduce treatment adherence and …

Inflammatory bowel diseases (IBD) are chronic inflammatory conditions of the
gastrointestinal tract. IBD are associated with a high prevalence of cognitive, behavioural …

Chronic pain is a disease of long-lasting pain with unpleasant feelings mediated by central
and (or) peripheral sensitization, its duration usually lasts more than 3 months or longer than …

The chronic neurological aspects of traumatic brain injury, post‐stroke syndromes, long
COVID‐19, persistent Lyme disease, and influenza encephalopathy having close …