Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine

MS de Almeida, E Susnik, B Drasler… - Chemical society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

[HTML][HTML] Cellular and functional heterogeneity of the airway epithelium

JD Davis, TP Wypych - Mucosal immunology, 2021 - Elsevier
The airway epithelium protects us from environmental insults, which we encounter with
every breath. Not only does it passively filter large particles, it also senses potential danger …

Identification of potent antimicrobial peptides via a machine-learning pipeline that mines the entire space of peptide sequences

J Huang, Y Xu, Y Xue, Y Huang, X Li, X Chen… - Nature Biomedical …, 2023 - nature.com
Systematically identifying functional peptides is difficult owing to the vast combinatorial
space of peptide sequences. Here we report a machine-learning pipeline that mines the …

[HTML][HTML] Biosafety of mesoporous silica nanoparticles; towards clinical translation

A Lérida-Viso, A Estepa-Fernández… - Advanced Drug Delivery …, 2023 - Elsevier
Mesoporous silica nanoparticles (MSNs) have attracted the attention of chemists, who have
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …

Non-invasive delivery strategies for biologics

AC Anselmo, Y Gokarn, S Mitragotri - Nature Reviews Drug Discovery, 2019 - nature.com
Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …

Advances in biomaterials for drug delivery

OS Fenton, KN Olafson, PS Pillai… - Advanced …, 2018 - Wiley Online Library
Advances in biomaterials for drug delivery are enabling significant progress in biology and
medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists …

Specific targeting cancer cells with nanoparticles and drug delivery in cancer therapy

S Raj, S Khurana, R Choudhari, KK Kesari… - Seminars in cancer …, 2021 - Elsevier
Nanotechnology has been the latest approach for diagnosis and treatment for cancer, which
opens up a new alternative therapeutic drug delivery option to treat disease. Nanoparticles …

Nanocrystals as a master key to deliver hydrophobic drugs via multiple administration routes

MB McGuckin, J Wang, R Ghanma, N Qin… - Journal of Controlled …, 2022 - Elsevier
The poor aqueous solubility of many approved drugs and most new chemical entities poses
a challenge to drug delivery scientists working in academic and industrial labs. Despite the …

Therapeutic efficacy of nanoparticles and routes of administration

D Chenthamara, S Subramaniam… - Biomaterials …, 2019 - spj.science.org
In modern-day medicine, nanotechnology and nanoparticles are some of the indispensable
tools in disease monitoring and therapy. The term “nanomaterials” describes materials with …

Mesoporous silica nanoparticles for pulmonary drug delivery

A Garcia-Fernandez, F Sancenon… - Advanced Drug Delivery …, 2021 - Elsevier
Over the last years, respiratory diseases represent a clinical concern, being included among
the leading causes of death in the world due to the lack of effective lung therapies, mainly …