microRNA‐based diagnostic and therapeutic applications in cancer medicine

LF Sempere, AS Azmi, A Moore - Wiley Interdisciplinary …, 2021 - Wiley Online Library
It has been almost two decades since the first link between microRNAs and cancer was
established. In the ensuing years, this abundant class of short noncoding regulatory RNAs …

Circulating miRNAs in breast cancer diagnosis and prognosis

B Cardinali, R Tasso, P Piccioli, MC Ciferri, R Quarto… - Cancers, 2022 - mdpi.com
Simple Summary In the era of precision medicine, new tools for better management of breast
cancer patients are still needed. From this perspective, circulating microRNA (miRNA), a …

[HTML][HTML] Salivary exosomal miR-24-3p serves as a potential detective biomarker for oral squamous cell carcinoma screening

L He, F Ping, Z Fan, C Zhang, M Deng, B Cheng… - Biomedicine & …, 2020 - Elsevier
Objectives miRNAs in salivary exosomes are used as novel non-invasive biomarkers for
detection strategies of human disease. Here, we aimed to investigate the diagnostic …

Multiple microRNAs as biomarkers for early breast cancer diagnosis

JY Jang, YS Kim, KN Kang… - Molecular and …, 2021 - spandidos-publications.com
MicroRNA (miRNA or miR) is stably present in plasma. It has been reported that miRNA
could be used for detecting cancer. Circulating miRNAs are being increasingly recognized …

Development and validation of a circulating microRNA panel for the early detection of breast cancer

R Zou, SY Loke, YC Tang, HP Too, L Zhou… - British journal of …, 2022 - nature.com
Background Mammography is widely used for breast cancer screening but suffers from a
high false-positive rate. Here, we perform the largest comprehensive, multi-center study to …

Cancer‐associated fibroblast‐derived exosomal microRNA‐24‐3p enhances colon cancer cell resistance to MTX by down‐regulating CDX2/HEPH axis

HW Zhang, Y Shi, JB Liu, HM Wang… - Journal of cellular …, 2021 - Wiley Online Library
Abstract MicroRNA‐24‐3p (miR‐24‐3p) has been implicated as a key promoter of
chemotherapy resistance in numerous cancers. Meanwhile, cancer‐associated fibroblasts …

Circulating miRNAs as diagnostic and prognostic biomarkers in common solid tumors: focus on lung, breast, prostate cancers, and osteosarcoma

M Bottani, G Banfi, G Lombardi - Journal of clinical medicine, 2019 - mdpi.com
An early cancer diagnosis is essential to treat and manage patients, but it is difficult to
achieve this goal due to the still too low specificity and sensitivity of classical methods …

High expression of microRNA-143 is associated with favorable tumor immune microenvironment and better survival in estrogen receptor positive breast cancer

Y Tokumaru, M Asaoka, M Oshi, E Katsuta… - International journal of …, 2020 - mdpi.com
microRNA-143 (miR-143) is a well-known tumor suppressive microRNA that exhibits anti-
tumoral function by targeting KRAS signaling pathways in various malignancies. We …

[HTML][HTML] Liquid biopsy for breast cancer using extracellular vesicles and cell-free microRNAs as biomarkers

PMM Ozawa, TS Jucoski, E Vieira, TM Carvalho… - Translational …, 2020 - Elsevier
Improvement of breast cancer (BC) patient's outcome is directly related to early detection.
However, there is still a lack of reliable biomarkers for diagnosis, prognosis and, treatment …

The role of MicroRNAs in breast cancer and the challenges of their clinical application

JP Muñoz, P Pérez-Moreno, Y Pérez, GM Calaf - Diagnostics, 2023 - mdpi.com
MicroRNAs (miRNAs) constitute a subclass of non-coding RNAs that exert substantial
influence on gene-expression regulation. Their tightly controlled expression plays a pivotal …