Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT): patient characteristics, treatment, and outcome—a systematic review

FSPL Wens, CCC Hulsker, M Fiocco, J Zsiros… - Cancers, 2023 - mdpi.com
Simple Summary Small-cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare
and aggressive ovarian cancer with a poor prognosis, and information on adequate …

[HTML][HTML] SMARCA4 and SMARCA2 co-deficiency: An uncommon molecular signature defining a subset of rare, aggressive and undifferentiated malignancies …

NR Field, KA Dickson, NT Nassif, DJ Marsh - Cancer Letters, 2024 - Elsevier
Genetic mutations and epigenetic modifications affecting multiple cancer-related genes
occur synergistically to drive tumorigenesis. Across a wide spectrum of cancers, pathogenic …

[HTML][HTML] Aberrant SWI/SNF Complex Members Are Predominant in Rare Ovarian Malignancies—Therapeutic Vulnerabilities in Treatment-Resistant Subtypes

Y Ma, NR Field, T Xie, S Briscas, EG Kokinogoulis… - Cancers, 2024 - mdpi.com
Simple Summary The rare ovarian cancer subtypes ovarian clear cell carcinoma (OCCC)
and Small cell carcinoma of the ovary, hypercalcaemic type (SCCOHT), can have mutations …

The fork remodeler helicase-like transcription factor in cancer development: All at once

Y Waheed, A Mojumdar, M Shafiq, A De Marco… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Abstract The Helicase-like Transcription Factor (HLTF) is a member of the SNF2-family of
fork remodelers, primarily studied for its capacity to provide DNA Damage Tolerance (DDT) …

A pan-cancer single-cell transcriptional analysis of antigen-presenting cancer-associated fibroblasts in the tumor microenvironment

J Chen, R Chen, J Huang - Frontiers in Immunology, 2024 - frontiersin.org
Background Cancer-associated fibroblasts (CAFs) are the primary stromal cells found in
tumor microenvironment, and display high plasticity and heterogeneity. By using single-cell …

SMASH: Scalable Method for Analyzing Spatial Heterogeneity of genes in spatial transcriptomics data

S Seal, BG Bitler, D Ghosh - PLoS Genetics, 2023 - journals.plos.org
In high-throughput spatial transcriptomics (ST) studies, it is of great interest to identify the
genes whose level of expression in a tissue covaries with the spatial location of cells/spots …

Rhabdoid tumor predisposition syndrome: A historical review of treatments and outcomes for associated pediatric malignancies

S Andres, K Huang, M Shatara… - Pediatric Blood & …, 2024 - Wiley Online Library
Rhabdoid tumor predisposition syndrome (RTPS) is a rare disorder associated with
malignant rhabdoid tumor of the kidney (RTK), atypical teratoid rhabdoid tumor (ATRT) …

Adding Highly Variable Genes to Spatially Variable Genes Can Improve Cell Type Clustering Performance in Spatial Transcriptomics Data

Y Li, S Stanojevic, B He, Z Jing, Q Huang, J Kang… - 2024 - researchsquare.com
Spatial transcriptomics has allowed researchers to analyze transcriptome data in its tissue
sample's spatial context. Various methods have been developed for detecting spatially …

[PDF][PDF] BBA-Molecular Basis of Disease

Y Waheed, A Mojumdar, M Shafiq, A de Marco… - researchgate.net
ABSTRACT The Helicase-like Transcription Factor (HLTF) is a member of the SNF2-family of
fork remodelers, primarily studied for its capacity to provide DNA Damage Tolerance (DDT) …