The absolute reliance of the mammalian brain on oxygen to generate ATP renders it acutely
vulnerable to hypoxia, whether at high altitude or in clinical settings of anemia or pulmonary …

Neurodegeneration (NDG) is linked with the progressive loss of neural function with
intellectual and/or motor impairment. Several diseases affecting older individuals, including …

Alzheimer's disease (AD) is the most common neurodegenerative disease mainly caused by
abnormal tau phosphorylation, amyloid β (Aβ) deposition and neuroinflammation. As an …

New Findings What is the topic of this review? Remote ischaemic preconditioning (RIPC)
and hypoxic preconditioning as novel therapeutic approaches for cardiac and …

Background Obstructive sleep apnea, characterized by sleep fragmentation and chronic
intermittent hypoxia (CIH), is a risk factor for Alzheimer's disease (AD) progression. Recent …

Chronic hypoxia is considered as one of the important environmental factors contributing to
the pathogenesis of Alzheimer's disease (AD). Many chronic hypoxia-causing comorbidities …

Individuals with sleep apnea often exhibit changes in cognitive behaviors consistent with
alterations in the hippocampus. It is hypothesized that adult neurogenesis in the dentate …

Obstructive sleep apnea (OSA) is a chronic and highly prevalent condition characterized by
chronic intermittent hypoxia (IH) and sleep fragmentation (SF), and can lead to a vast array …

Tauopathies are a group of neurodegenerative diseases whose central feature is
dysfunction of the microtubule-associated protein tau (MAPT). Although the exact etiology of …

Developing cellular models of sporadic Alzheimer's disease (sAD) is challenging due to the
unknown initiator of disease onset and the slow disease progression that takes many years …