Molecular dynamics simulation of protein and protein–ligand complexes
R Shukla, T Tripathi - Computer-aided drug design, 2020 - Springer
Biomacromolecules, including proteins and their complexes, adopt multiple conformations
that are linked to their biological functions. Though some of the structural heterogeneity can …
that are linked to their biological functions. Though some of the structural heterogeneity can …
Structural analysis of biomacromolecules using circular dichroism spectroscopy
X Zhao, Y Wang, D Zhao - … Methods to Study Biomolecular Structure and …, 2023 - Elsevier
The chirality of biomacromolecules renders circular dichroism (CD) detection a method to
measure their multiscale structures. This chapter reviews the applications of CD …
measure their multiscale structures. This chapter reviews the applications of CD …
[图书][B] Advances in protein molecular and structural biology methods
T Tripathi, VK Dubey - 2022 - books.google.com
Advances in Protein Molecular and Structural Biology Methods offers a complete overview of
the latest tools and methods applicable to the study of proteins at the molecular and …
the latest tools and methods applicable to the study of proteins at the molecular and …
Therapeutic protein-based vaccines
Infectious diseases are reported worldwide, and the emergence of highly mutated antibiotic-
resistant strains is a major concern globally. Developing efficient vaccines is the only way to …
resistant strains is a major concern globally. Developing efficient vaccines is the only way to …
Investigating Multi-Target Antiviral Compounds by Screening of Phytochemicals From Neem (Azadirachta indica) Against PRRSV: A Vetinformatics Approach
Porcine reproductive and respiratory syndrome virus (PRRSV) is a global health problem for
pigs. PRRSV is highly destructive and responsible for significant losses to the swine …
pigs. PRRSV is highly destructive and responsible for significant losses to the swine …
Increasing the Modulation Depth of GdIII-Based Pulsed Dipolar EPR Spectroscopy (PDS) with Porphyrin–GdIII Laser-Induced Magnetic Dipole Spectroscopy
Distance determination with pulsed EPR has become an important technique for the
structural investigation of biomacromolecules, with double electron–electron resonance …
structural investigation of biomacromolecules, with double electron–electron resonance …
Strategies to improve the expression and solubility of recombinant proteins in E. coli
N Nag, H Khan, T Tripathi - Advances in protein molecular and structural …, 2022 - Elsevier
With the development of recombinant DNA technology in the 1980s, the heterologous
expression of proteins has emerged as a valuable tool for researchers and pharmaceutical …
expression of proteins has emerged as a valuable tool for researchers and pharmaceutical …
Unraveling structural and conformational dynamics of DGAT1 missense nsSNPs in dairy cattle
Cattle are domestic animals that have been nourishing humans for thousands of years. Milk
from cattle represents a key source of high-quality protein, fat, and other nutrients. The …
from cattle represents a key source of high-quality protein, fat, and other nutrients. The …
Computational approaches in drug discovery and design
Drug discovery is an expensive and complicated process. The drug must fulfill some criteria
of being nontoxic, bioavailable, and potent. In the view of evermore stringent demands about …
of being nontoxic, bioavailable, and potent. In the view of evermore stringent demands about …
The nucleotide excision repair proteins through the lens of molecular dynamics simulations
Mutations that affect the proteins responsible for the nucleotide excision repair (NER)
pathway can lead to diseases such as xeroderma pigmentosum, trichothiodystrophy …
pathway can lead to diseases such as xeroderma pigmentosum, trichothiodystrophy …