The role of MRI differs considerably between the three main groups of hematological
malignancies: lymphoma, leukemia, and myeloma. In myeloma, whole‐body MRI (WB‐MRI) …

In response to the changing availability of nutrients and oxygen in the bone marrow
microenvironment, acute myeloid leukemia (AML) cells continuously adjust their metabolic …

Classical BCR-ABL-negative myeloproliferative neoplasms (MPN) are a heterogeneous
group of hematologic malignancies, including essential thrombocythemia (ET), polycythemia …

Purpose TMI utilizes IMRT to deliver organ sparing targeted radiotherapy in patients
undergoing hematopoietic cell transplantation (HCT). TMI addresses an unmet need …

Purpose Total marrow irradiation (TMI) has significantly advanced radiation conditioning for
hematopoietic cell transplantation in hematological malignancies by reducing conditioning …

Purpose: Acute myeloid leukemia (AML) is a highly aggressive form of leukemia, which
results in poor survival outcomes. Currently, diagnosis and prognosis are based on invasive …

Objective: Active bone marrow (ABM) can serve as both an organ at risk and a target in
external beam radiotherapy. 18F-fluorothymidine (FLT) PET is the current gold standard for …

Jennifer Holter-Chakrabarty, MD, is a professor of medicine in the section of
hematology/oncology at the University of Oklahoma Health Sciences Center. She is also an …

Purpose Total body irradiation (TBI) has been widely utilized as part of the conditioning
regimen for hematopoietic stem cell transplantation (HSCT), but is associated with …

X-ray computed tomography (CT) in PET/CT is commonly operated with a single energy,
resulting in a limitation of lacking tissue composition information. Dual-energy (DE) spectral …