The immune system is generally known to be the primary defense mechanism against
pathogens. Any pathological conditions are reflected in anomalies in the immune system …

Chemokines are known to be immunoregulatory proteins involved not only in lymphocyte
chemotaxis to the site of inflammation, but also in neuromodulation, neurogenesis, and …

Objective Immune system dysfunction is hypothesised to contribute to structural brain
changes through aberrant synaptic pruning in schizophrenia. However, evidence is mixed …

Although there is convergent evidence for blood-brain barrier (BBB) dysfunction and
peripheral inflammation in schizophrenia (SZ) and bipolar disorder (BD), it is unknown …

A potential relationship between dysregulation of immune/inflammatory pathways and
cognitive impairment has been suggested in severe mental illnesses (SMI), such as …

Introduction High-inflammation subgroups of patients with psychosis demonstrate cognitive
deficits and neuroanatomical alterations. Systemic inflammation assessed using IL-6 and C …

Schizophrenia (SZ) and bipolar disorder (BD) are characterized by major symptomatic,
cognitive, and neuroanatomical changes. Recent studies have used optical coherence …

Human endogenous retroviruses (ERVs) are ancestorial retroviral elements that were
integrated into our genome through germline infections and insertions during evolution …

Recent findings link cognitive impairment and inflammatory-immune dysregulation in
schizophrenia (SZ) and bipolar (BD) spectrum disorders. However, heterogeneity and …

Immunopsychiatric field has rapidly accumulated evidence demonstrating the involvement of
both innate and adaptive immune components in psychotic disorders such as …