An insight into medicinal attributes of dithiocarbamates: Bird's eye view

SD Shinde, AP Sakla, N Shankaraiah - Bioorganic Chemistry, 2020 - Elsevier
Dithiocarbamates are considered as an important motif owing to its extensive biological
applications in medicinal chemistry. The synthesis of this framework can easily be achieved …

Application of dithiocarbamates as potential new antitrypanosomatids-drugs: Approach chemistry, functional and biological

JWF Oliveira, HAO Rocha, WMTQ de Medeiros… - Molecules, 2019 - mdpi.com
Dithiocarbamates represent a class of compounds that were evaluated in different
biomedical applications because of their chemical versatility. For this reason, several …

Curcumin hybrid molecules for the treatment of Alzheimer's disease: Structure and pharmacological activities

WB Zang, HL Wei, WW Zhang, W Ma, J Li… - European Journal of …, 2023 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease among the
elderly. Contemporary treatments can only relieve symptoms but fail to delay disease …

Curcumin‐based bioactive heterocycles derived via multicomponent reactions

AA Nagargoje, MH Shaikh… - Archiv der Pharmazie, 2023 - Wiley Online Library
Curcumin is an important phytochemical, found in the Asian countries, especially in the
Indian subcontinent. The use of this “privileged natural product” in the diversity‐oriented …

Synthesis and bio-properties of 4-piperidone containing compounds as curcumin mimics

AS Girgis, P D'Arcy, DR Aboshouk, MS Bekheit - RSC advances, 2022 - pubs.rsc.org
The broad spectrum of curcumin's beneficial properties has encouraged medicinal
researchers to investigate its therapeutic efficacy against diverse diseases. The clinical …

Synthesis, in-silico antiviral screening and in-vitro antibacterial screening of a novel chalcone derivatives

A Uniyal, BK Thakur, S Singh, J Gairolla… - Journal of the Indian …, 2023 - Elsevier
A new series of novel chalcones was synthesized and subjected to screening of theoretical
molecular and biological properties. For evaluating the theoretical molecular properties of …

In (OTf) 3 catalysed an expeditious synthesis of β-carboline–imidazo [1, 2-a] pyridine and imidazo [1, 2-a] pyrazine conjugates

N Devi, D Singh, S Mor, S Chaudhary, RK Rawal… - RSC …, 2016 - pubs.rsc.org
β-Carboline containing alkaloids are ubiquitously present in Nature, while imidazo [1, 2-a]
pyridine nucleus is incorporated in various synthetic commercial drugs and biologically …

Synthesis and anti-tumor activity of EF24 analogues as IKKβ inhibitors

R Jin, Q Chen, S Yao, E Bai, W Fu, L Wang… - European Journal of …, 2018 - Elsevier
EF24 is an IKKβ inhibitor (IC 50: 72 μM) containing various anti-tumor activities. In this study,
a series of EF24 analogs targeting IKKβ were designed and synthesized. Several IKKβ …

A magnetically recyclable iron oxide-supported copper oxide nanocatalyst (Fe 3 O 4–CuO) for one-pot synthesis of S-aryl dithiocarbamates under solvent-free …

F Aryanasab - RSC advances, 2016 - pubs.rsc.org
A green, convenient and efficient procedure is reported for the synthesis of S-aryl
dithiocarbamates by a simple one-pot three component Ullmann-type condensation of an …

An Expeditious Approach for the Synthesis of β‐Carboline− Pyrazole‐Based Molecular Hybrids

D Singh, P Sharma, R Kumar… - Asian Journal of …, 2018 - Wiley Online Library
A simple and highly efficient one‐pot, metal‐free approach has been developed for the
synthesis of β‐carboline− pyrazole/− pyrazoline‐based molecular hybrids. The synthesis of …