In a research environment dominated by reductionist approaches to brain disease
mechanisms, gene network analysis provides a complementary framework in which to tackle …

The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …

Cervical cancer is the third most common malignancy in women worldwide. It remains a
leading cause of cancer-related death for women in developing countries. In order to …

BACKGROUND Extracellular microRNAs (miRNAs) have been proposed as potentially
robust and stable biomarkers of various disease conditions. The primary objective of this …

Background Bladder cancer is the most common malignant tumor of the urinary system and
it is a heterogeneous disease with both superficial and invasive growth. However, its …

Purpose Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with
a dismal prognosis which is, among others, due to a lack of suitable biomarkers and …

Motivation Differential co-expression analysis (DCEA) has emerged in recent years as a
novel, systematic investigation into gene expression data. While most DCEA studies or tools …

Background MicroRNAs (miRNAs) emerged as regulatory elements, with up to 70% of all
miRNAs found in the brain, playing key roles in the onset of Alzheimer's disease (AD) …

Chronic cerebral hypoperfusion‐derived brain damage contributes to the progression of
vascular cognitive impairment and dementia (VCID). Cumulative evidence has shown that …

MicroRNAs (miRNAs) can notably control many targets each and regulate entire cellular
pathways, but whether miRNAs can regulate complete neurotransmission processes is …