Obesity and dyslipidemia

J Vekic, A Zeljkovic, A Stefanovic, Z Jelic-Ivanovic… - Metabolism, 2019 - Elsevier
Obesity, a pandemic of the modern world, is intimately associated with dyslipidemia, which
is mainly driven by the effects of insulin resistance and pro-inflammatory adipokines …

Epigallocatechin-3-Gallate (EGCG): New therapeutic perspectives for neuroprotection, aging, and neuroinflammation for the modern age

A Payne, S Nahashon, E Taka, GM Adinew… - Biomolecules, 2022 - mdpi.com
Alzheimer's and Parkinson's diseases are the two most common forms of neurodegenerative
diseases. The exact etiology of these disorders is not well known; however, environmental …

Molecular choreography of acute exercise

K Contrepois, S Wu, KJ Moneghetti, D Hornburg… - Cell, 2020 - cell.com
Acute physical activity leads to several changes in metabolic, cardiovascular, and immune
pathways. Although studies have examined selected changes in these pathways, the system …

Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α production

AC Tosello-Trampont, SG Landes, V Nguyen… - Journal of Biological …, 2012 - ASBMB
Nonalcoholic steatohepatitis (NASH), characterized by lipid deposits within hepatocytes
(steatosis), is associated with hepatic injury and inflammation and leads to the development …

Insulin signalling mechanisms for triacylglycerol storage

MP Czech, M Tencerova, DJ Pedersen, M Aouadi - Diabetologia, 2013 - Springer
Insulin signalling is uniquely required for storing energy as fat in humans. While de novo
synthesis of fatty acids and triacylglycerol occurs mostly in liver, adipose tissue is the primary …

Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation

X Liu, Y Liang, R Song, G Yang, J Han, Y Lan, S Pan… - Molecular cancer, 2018 - Springer
Background Abnormal metabolism, including abnormal lipid metabolism, is a hallmark of
cancer cells. Some studies have demonstrated that the lipogenic pathway might promote the …

Lipolysis in lipid turnover, cancer cachexia, and obesity-induced insulin resistance

P Arner, D Langin - Trends in Endocrinology & Metabolism, 2014 - cell.com
Triglycerides in adipose tissue are rapidly mobilized during times of energy needs via
lipolysis, a catabolic process that plays important role in whole body triglyceride turnover …

Probing the links: Long non-coding RNAs and NF-κB signalling in atherosclerosis

MS Hussain, O Afzal, G Gupta, ASA Altamimi… - … -Research and Practice, 2023 - Elsevier
Atherosclerosis is a chronic inflammatory disease that involves the accumulation of lipids
and immune cells in the arterial wall. NF-kB signaling is a key regulator of inflammation and …

Mannan-oligosaccharide modulates the obesity and gut microbiota in high-fat diet-fed mice

H Wang, X Zhang, S Wang, H Li, Z Lu, J Shi, Z Xu - Food & function, 2018 - pubs.rsc.org
The gut microbiota is considered to be associated with high-fat diet (HFD)-induced obesity
and metabolic syndrome (MS). Mannan-oligosaccharide (MOS) is widely used as a natural …

[HTML][HTML] Plastic nanoparticles cause mild inflammation, disrupt metabolic pathways, change the gut microbiota and affect reproduction in zebrafish: A full generation …

MH Marana, R Poulsen, EA Thormar… - Journal of Hazardous …, 2022 - Elsevier
Plastic pollution has become a major concern on a global scale. The plastic is broken down
into minuscule particles, which have an impact on the biosystems, however long-term …