[HTML][HTML] Signaling in autism: Relevance to nutrients and sex

YP Hsueh - Current Opinion in Neurobiology, 2025 - Elsevier
Highlights•Synaptic transmission and signaling are critical for autism spectrum
disorders.•Zinc mediates presynaptic signals to trigger postsynaptic responses.•Branched …

Understanding the role of AMPA receptors in autism: insights from circuit and synapse dysfunction

A Jimenez-Gomez, MX Nguyen, JS Gill - Frontiers in Psychiatry, 2024 - frontiersin.org
Autism spectrum disorders represent a diverse etiological spectrum that converge on a
syndrome characterized by discrepant deficits in developmental domains often highlighted …

Differential effectiveness of dietary zinc supplementation with autism-related behaviours in Shank2 knockout mice

K Lee, Y Jung, Y Vyas, Z Mills… - Philosophical …, 2024 - royalsocietypublishing.org
The family of SHANK proteins have been shown to be critical in regulating glutamatergic
synaptic structure, function and plasticity. SHANK variants are also prevalent in autism …

Turn‐on Solid‐State Fluorescent Determination of Zinc Ion by Quinoline‐based Covalent Organic Framework

P García‐Arroyo, E Gala… - Macromolecular …, 2024 - Wiley Online Library
A new quinoline‐based COF (Covalent Organic Framework), obtained by Povarov reaction,
containing 2, 6‐diisopropylphenyl moieties as substituents over the heterocyclic ring is …

Neural Network Excitation/Inhibition: A Key to Empathy and Empathy Impairment

Y Tang, C Wang, Q Li, G Liu, D Song… - The …, 2024 - journals.sagepub.com
Empathy is an ability to fully understand and feel the mental states of others. We emphasize
that empathy is elicited by the transmission of pain, fear, and sensory information. In clinical …

[HTML][HTML] Corticosteroids and the Pharmacological Management of Autism—An Integrative Review

LAG de Jesus, G Piuvezam, IDSF Pimenta… - Scientia …, 2024 - mdpi.com
Autism spectrum disorder (ASD), or autism, is a lifelong neurodevelopmental condition
typically detected during early childhood, for which no specific and efficient pharmacological …

[HTML][HTML] Advances in the Treatment of Autism Spectrum Disorder: Current and Promising Strategies

K Yenkoyan, Z Ounanian, M Mirumyan… - Current medicinal …, 2024 - ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is an umbrella term for developmental disorders
characterized by social and communication impairments, language difficulties, restricted …

[HTML][HTML] Key Synaptic Pathology in Autism Spectrum Disorder: Genetic Mechanisms and Recent Advances

Y Zhang, R Tang, ZM Hu, XH Wang, X Gao… - Journal of Integrative …, 2024 - imrpress.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
impaired social interactions and verbal communication, accompanied by symptoms of …

Unravelling the role of SHANK3 mutations in targeted therapies for autism spectrum disorders

X Li - Discover Psychology, 2024 - Springer
Abstract Autism Spectrum Disorder (ASD) presents a significant challenge due to its
complex genetic basis and associated comorbidities. Among the genes implicated in ASD …

Deficiency of the histone lysine demethylase KDM5B causes autism-like phenotypes via increased NMDAR signalling

L Pérez-Sisqués, SU Bhatt, A Caruso, MU Ahmed… - bioRxiv, 2024 - biorxiv.org
Loss-of-function mutations in genes encoding lysine methyltransferases (KMTs) and
demethylases (KDMs) responsible for regulating the trimethylation of histone 3 on lysine 4 …