Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …

The mitochondrial inner membrane contains a large protein complex that functions in inner
membrane organization and formation of membrane contact sites. The complex was variably …

The elaborate membrane architecture of mitochondria is a prerequisite for efficient
respiration and ATP generation. The cristae membranes, invaginations of the inner …

Mitofilin proteins are crucial organizers of mitochondrial architecture. They are located in the
inner mitochondrial membrane and interact with several protein complexes of the outer …

A decrease in adult hippocampal neurogenesis has been linked to age-related cognitive
impairment. However, the mechanisms involved in this age-related reduction remain …

The aging brain suffers mitochondrial dysfunction and a reduced availability of energy in the
form of ATP, which in turn may cause or promote the decline in cognitive, sensory, and motor …

Genomic damage can feature DNA-protein crosslinks whereby their acute accumulation is
utilized to treat cancer and progressive accumulation causes neurodegeneration. This is …

Mitofilin, also known as heart muscle protein, is an inner mitochondrial membrane structural
protein that plays a central role in maintaining cristae morphology and structure. It is a critical …

Although steady progress on understanding brain aging has been made over recent
decades through standard anatomical, immunohistochemical, and biochemical techniques …

Human mitofilin is a mitochondrial protein that controls cristae formation. Here, we
investigated the role of the Caenorhabditis elegans mitofilin homologs, IMMT‐1 and‐2, in …