Hemolysis is a pathological feature of several diseases of diverse etiology such as
hereditary anemias, malaria, and sepsis. A major complication of hemolysis involves the …

Lactoferrin is a nutrient classically found in mammalian milk. It binds iron and is transferred
via a variety of receptors into and between cells, serum, bile, and cerebrospinal fluid. It has …

Pregnancy-induced hypertension and preeclampsia are associated with significant maternal
and fetal mortality. A better understanding of these diseases, delineation of molecular …

Systemic inflammation, circulating immune cell activation, and endothelial cell damage play
a critical role in vascular pathogenesis. Flavonoids have shown anti-inflammatory effects. In …

The combination of inflammation and thrombosis is a hallmark of many cardiovascular
diseases. Under such conditions, platelets are recruited to an area of inflammation by …

A key inflammatory mechanism recently identified in platelets involves the Nod-like receptor
nucleotide-binding domain leucine-rich repeat containing protein 3 (NLRP3) and Bruton …

Background The high incidence of thrombotic events is one of the clinical characteristics of
coronavirus disease of 2019 (COVID-19), due to a hyperinflammatory response caused by …

Inflammasome complex is a multimeric protein comprising of upstream sensor protein of
nucleotide-binding oligomerization domain (NOD)-like receptor family. It has an adaptor …

Inflammasomes are intracellular multimeric complexes that cleave the precursors of the IL-1
family of cytokines and various proteins, found predominantly in cells of hematopoietic …

Thrombosis is one of the leading causes of death worldwide. As such, it also occurs as one
of the major complications in hemolytic diseases, like hemolytic uremic syndrome …