The Bayesian revolution in genetics
MA Beaumont, B Rannala - Nature Reviews Genetics, 2004 - nature.com
Bayesian statistics allow scientists to easily incorporate prior knowledge into their data
analysis. Nonetheless, the sheer amount of computational power that is required for …
analysis. Nonetheless, the sheer amount of computational power that is required for …
A survey of DNA motif finding algorithms
MK Das, HK Dai - BMC bioinformatics, 2007 - Springer
Background Unraveling the mechanisms that regulate gene expression is a major challenge
in biology. An important task in this challenge is to identify regulatory elements, especially …
in biology. An important task in this challenge is to identify regulatory elements, especially …
[图书][B] Monte Carlo strategies in scientific computing
JS Liu, JS Liu - 2001 - Springer
This book provides a self-contained and up-to-date treatment of the Monte Carlo method
and develops a common framework under which various Monte Carlo techniques can be" …
and develops a common framework under which various Monte Carlo techniques can be" …
Genesis: cluster analysis of microarray data
A Sturn, J Quackenbush, Z Trajanoski - Bioinformatics, 2002 - academic.oup.com
A versatile, platform independent and easy to use Java suite for large-scale gene
expression analysis was developed. Genesis integrates various tools for microarray data …
expression analysis was developed. Genesis integrates various tools for microarray data …
The Spo0A regulon of Bacillus subtilis
The master regulator for entry into sporulation in Bacillus subtilis is the DNA‐binding protein
Spo0A, which has been found to influence, directly or indirectly, the expression of over 500 …
Spo0A, which has been found to influence, directly or indirectly, the expression of over 500 …
An integrated software system for analyzing ChIP-chip and ChIP-seq data
We present CisGenome, a software system for analyzing genome-wide chromatin
immunoprecipitation (ChIP) data. CisGenome is designed to meet all basic needs of ChIP …
immunoprecipitation (ChIP) data. CisGenome is designed to meet all basic needs of ChIP …
Computational identification of cis-regulatory elements associated with groups of functionally related genes in Saccharomyces cerevisiae
AlignACE is a Gibbs sampling algorithm for identifying motifs that are over-represented in a
set of DNA sequences. When used to search upstream of apparently coregulated genes …
set of DNA sequences. When used to search upstream of apparently coregulated genes …
BioProspector: discovering conserved DNA motifs in upstream regulatory regions of co-expressed genes
The development of genome sequencing and DNA microarray analysis of gene expression
gives rise to the demand for data-mining tools. BioProspector, a C program using a Gibbs …
gives rise to the demand for data-mining tools. BioProspector, a C program using a Gibbs …
Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation
Whole-genome mRNA quantitation can be used to identify the genes that are most
responsive to environmental or genotypic change. By searching for mutually similar DNA …
responsive to environmental or genotypic change. By searching for mutually similar DNA …
Genomic targets of nuclear estrogen receptors
R O'Lone, MC Frith, EK Karlsson… - Molecular …, 2004 - academic.oup.com
Estrogen influences the physiology of many target tissues in both women and men. The long-
term effects of estrogen are mediated predominantly by nuclear estrogen receptors (ERs) …
term effects of estrogen are mediated predominantly by nuclear estrogen receptors (ERs) …