The rewarding properties of social interactions are essential for the expression of social
behavior and the development of adaptive social relationships. Here, we review sex …

Drug addiction is a multifactorial disorder resulting from the complex interaction between
biological, environmental and drug-induced effects. Generally, stress is a well-known risk …

Cross-species research suggests that exploratory behaviors increase during adolescence
and relate to the social, affective, and risky behaviors characteristic of this developmental …

Variation within mesolimbic dopamine (DA) pathways has significant implications for
behavioral responses to rewards, and previous studies have indicated long‐term …

Natural and drug rewards act on the same neural pathway, the mesolimbic dopaminergic
system. In brain regions such as the nucleus accumbens and ventral tegmental area, drugs …

We previously developed rat experimental models based on the conditioned place
preference (CPP) paradigm in which only four 15-min episodes of dyadic social interaction …

Individuals suffering from substance use disorders often show severely impaired social
interaction, preferring drugs of abuse to the contact with others. Their impaired social …

The family members of the mitogen-activated protein kinases (MAPK) mediate a wide variety
of cellular behaviors in response to extracellular stimuli. p38 MAPKs are key signaling …

Many forms of joint action involve physical coupling between the participants, such as when
moving a sofa together or dancing a tango. We report the results of a novel two-person …

(1) Background: Positive social relationships are essential for mental and physical health.
However, not all individuals experience social interaction as a rewarding activity.(2) …