The addition of nanoparticles (NPs) to a polymer matrix, forming a polymer nanocomposite
(PNC), is known to alter the microscopic dynamic processes of both species which leads to …

It has long been axiomatic that a protein's structure determines its function. Intrinsically
disordered proteins (IDPs) and disordered protein regions (IDRs) defy this structure …

Phase separation is a ubiquitous and emerging mechanism underlying intracellular
organization. Yet how distinct molecular compositions in phase-separated condensates are …

Liquid-liquid phase separation is emerging as a crucial phenomenon in several
fundamental cell processes. A range of eukaryotic systems exhibit liquid condensates …

Inside prokaryotic cells, passive translational diffusion typically limits the rates with which
cytoplasmic proteins can reach their locations. Diffusion is thus fundamental to most cellular …

Despite their diverse biochemical characteristics and functions, all DNA-binding proteins
share the ability to accurately locate their target sites among the vast excess of non-target …

A topic of intense current investigation pursues the question of how the highly crowded
environment of biological cells affects the dynamic properties of passively diffusing particles …

Metabolic reactions in living cells are limited by diffusion of reagents in the cytoplasm. Any
attempt to quantify the kinetics of biochemical reactions in the cytosol should be preceded by …

Temperature variations have a big impact on bacterial metabolism and death, yet an
exhaustive molecular picture of these processes is still missing. For instance, whether …

We discuss a quantitative influence of macromolecular crowding on biological processes:
motion, bimolecular reactions, and gene expression in prokaryotic and eukaryotic cells. We …