Sequential multicomponent C–H bond addition is a powerful approach for the rapid,
modular generation of molecular complexity in a single reaction. In this approach, C–H …

Axially chiral allenes occur on a wide range of natural products and synthetic molecules with
significant biological activity. Furthermore, they are versatile building blocks in organic …

The merger of photoredox and transition-metal catalysis has evolved as a robust platform in
organic synthesis over the past decade. The stereoselective 1, 4-functionalization of 1, 3 …

Reactions involving allenyl ion intermediates have been widely applied in the synthesis of
functionalized allenes, but reactions involving allenyl radicals have been less studied and …

By employing CuOAc as the catalyst, we realize a four-component reaction of 1, 3-enynes,
diselenides, DABCO·(SO2) 2, and cycloketone oxime esters, providing facile access to …

Chiral organophosphorous compounds are very important in catalysis, organic syntheses,
and medicinal chemistry. However, catalytic enantioselective protocols for the axially chiral …

[3, 4]-Fused oxindoles are the core structures of the naturally occurring oxindole alkaloids,
and the fused tricyclic structures have distinguished themselves with unique biological …

Allenol has been identified as a versatile building block for organic synthesis, and numerous
efforts have been made to synthesize and apply allenol. However, limited efforts have been …

A Pd-catalyzed asymmetric higher-order dipolar cycloaddition between allenyl carbonates
and azadienes is achieved by exploiting novel alkylidene-π-allyl-Pd dipoles. This research …

We report the development of a new class of multifunctional chiral guanidine/Pd (0) catalyst
system for 1, 4-addition/arylation tandem reaction. A variety of tetra-substituted allenes were …