The rapid expansion of machine learning is offering a new wave of opportunities for nuclear
medicine. This paper reviews applications of machine learning for the study of attenuation …

Background Focused ultrasound (FUS)-mediated blood–brain barrier (BBB) opening has
shown efficacy in removal of amyloid plaque and improvement of cognitive functions in …

The two primary molecular pathologies in Alzheimer's disease are amyloid-β plaques and
tau-immunoreactive neurofibrillary tangles. Investigations into these pathologies have been …

Chronic pain patients present with cortical gray matter alterations, observed with anatomical
magnetic resonance (MR) imaging. Reduced regional gray matter volumes are often …

Alzheimer's disease (AD) patients are known to have heterogeneous clinical presentation
and pathologic patterns. We hypothesize that AD dementia can be categorized into subtypes …

When walking on a split-belt treadmill, where each leg is driven at a different speed, a
temporary change is made to the typical steady-state walking pattern. The exact ways in …

An imbalance between excitatory and inhibitory neurotransmission has been linked to
fibromyalgia (FM). Magnetic resonance spectroscopy has shown increased levels of …

Objective Cholinergic degeneration and β-amyloid contribute to brain atrophy and cognitive
dysfunction in Alzheimer disease (AD) and Lewy body disease (LBD), but their relationship …

Coexisting Alzheimer's disease (AD) pathology is common in patients with dementia with
Lewy bodies (DLB). To evaluate the cortical thinning in patients with DLB considering the …

Gait impairment during complex walking in older adults is thought to result from a
progressive failure to compensate for deteriorating peripheral inputs by central neural …