Glycation is a non-enzymatic post-translational modification of proteins, formed by the
reaction of reducing sugars and α-dicarbonyl products of their degradation with amino and …

Ever increasing information on genome and proteome has offered fascinating details and
new opportunities to understand the molecular biology. It is now known that histone proteins …

Glycation initiates with the non-enzymatic reaction of amino group of proteins and
lipoproteins by carbonyl group of sugar moiety and intermediates of glycative stress such as …

Advanced glycation end products are formed by non-enzymatic reactions between proteins
and carbohydrates, causing irreversible lysine and arginine alterations that severely affect …

Chromatin, the complex of DNA and histone proteins, serves as a main integrator of cellular
signals. Increasing evidence links cellular functional to chromatin state. Indeed, different …

Methylglyoxal (MG), a highly reactive dicarbonyl metabolite gets generated during glucose
oxidation and lipid peroxidation, which contributes to glycation. In type 2 diabetes mellitus …

Background: Advanced glycation end products (AGEs) in diabetic patients can trigger
several autoimmune responses. This article aims to assess the presence of circulating …

Abstract Kuromoji (Lindera umbellata Thunb.) is a deciduous shrub of the camphoraceae
family endemic to Japan. It has long been used as an ingredient for tea and essential oil …

Objective: The purpose of this study is to investigate the effects of anti-glycation activity of
kuromoji (Lindera umbellate Thunb.) extract (KE) on diabetic nephropathy. Methods: Using …

Introduction: Advanced glycation end-products (AGEs) are contributing factors to diabetes
complications. The antigenic nature of AGEs established the theory of incessant …