Monoclonal antibody therapy of herpes simplex virus: An opportunity to decrease congenital and perinatal infections

IM Backes, DA Leib, ME Ackerman - Frontiers in Immunology, 2022 - frontiersin.org
The fetal/neonatal period represents both a unique window of opportunity for interventions
as well as vulnerability to a number of viral infections. While Herpesviruses such as herpes …

Maternally transferred mAbs protect neonatal mice from HSV-induced mortality and morbidity

IM Backes, BK Byrd, MD Slein, CD Patel… - Journal of Experimental …, 2022 - rupress.org
Neonatal herpes simplex virus (nHSV) infections often result in significant mortality and
neurological morbidity despite antiviral drug therapy. Maternally transferred herpes simplex …