[HTML][HTML] Transcription factor exchange enables prolonged transcriptional bursts
W Pomp, JVW Meeussen, TL Lenstra - Molecular Cell, 2024 - cell.com
Single-molecule imaging inside living cells has revealed that transcription factors (TFs) bind
to DNA transiently, but a long-standing question is how this transient binding is related to …
to DNA transiently, but a long-standing question is how this transient binding is related to …
Dissecting the dynamics of coordinated active transcriptional repression in a multicellular organism
The ability to refine transcriptional levels via active repression in an euchromatic context
represents a critical regulatory process during development. While the molecular players of …
represents a critical regulatory process during development. While the molecular players of …
[HTML][HTML] Time will tell: comparing timescales to gain insight into transcriptional bursting
JVW Meeussen, TL Lenstra - Trends in Genetics, 2024 - cell.com
Recent imaging studies have captured the dynamics of regulatory events of transcription
inside living cells. These events include transcription factor (TF) DNA binding, chromatin …
inside living cells. These events include transcription factor (TF) DNA binding, chromatin …