Interstitial lung diseases

M Wijsenbeek, A Suzuki, TM Maher - The Lancet, 2022 - thelancet.com
Over 200 interstitial lung diseases, from ultra rare to relatively common, are recognised.
Most interstitial lung diseases are characterised by inflammation or fibrosis within the …

Idiopathic pulmonary fibrosis

FJ Martinez, HR Collard, A Pardo, G Raghu… - Nature reviews Disease …, 2017 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by
progressive lung scarring and the histological picture of usual interstitial pneumonia (UIP). It …

Pirfenidone in patients with unclassifiable progressive fibrosing interstitial lung disease: a double-blind, randomised, placebo-controlled, phase 2 trial

TM Maher, TJ Corte, A Fischer, M Kreuter… - The lancet Respiratory …, 2020 - thelancet.com
Background At present, no approved pharmacotherapies are available for unclassifiable
interstitial lung disease (ILD), which is characterised by progressive fibrosis of the lung. We …

Diagnosis of idiopathic pulmonary fibrosis. An official ATS/ERS/JRS/ALAT clinical practice guideline

G Raghu, M Remy-Jardin, JL Myers… - American journal of …, 2018 - atsjournals.org
Background: This document provides clinical recommendations for the diagnosis of
idiopathic pulmonary fibrosis (IPF). It represents a collaborative effort between the American …

Diagnostic criteria for idiopathic pulmonary fibrosis: a Fleischner Society White Paper

DA Lynch, N Sverzellati, WD Travis… - The Lancet respiratory …, 2018 - thelancet.com
This Review provides an updated approach to the diagnosis of idiopathic pulmonary fibrosis
(IPF), based on a systematic search of the medical literature and the expert opinion of …

Diagnostic accuracy of transbronchial lung cryobiopsy for interstitial lung disease diagnosis (COLDICE): a prospective, comparative study

LK Troy, C Grainge, TJ Corte, JP Williamson… - The lancet Respiratory …, 2020 - thelancet.com
Background Transbronchial lung cryobiopsy (TBLC) is a novel technique for sampling lung
tissue for interstitial lung disease diagnosis. The aim of this study was to establish the …

Presentation, diagnosis and clinical course of the spectrum of progressive-fibrosing interstitial lung diseases

V Cottin, NA Hirani, DL Hotchkin… - European …, 2018 - Eur Respiratory Soc
Although these conditions are rare, a proportion of patients with interstitial lung diseases
(ILDs) may develop a progressive-fibrosing phenotype. Progressive fibrosis is associated …

Interstitial lung abnormalities: state of the art

A Hata, ML Schiebler, DA Lynch, H Hatabu - Radiology, 2021 - pubs.rsna.org
The clinical importance of interstitial lung abnormality (ILA) is increasingly recognized. In
July 2020, the Fleischner Society published a position paper about ILA. The purposes of this …

Mechanisms of autoantibody-induced pathology

RJ Ludwig, K Vanhoorelbeke, F Leypoldt… - Frontiers in …, 2017 - frontiersin.org
Autoantibodies are frequently observed in healthy individuals. In a minority of these
individuals, they lead to manifestation of autoimmune diseases, such as rheumatoid arthritis …

Variability in global prevalence of interstitial lung disease

B Kaul, V Cottin, HR Collard, C Valenzuela - Frontiers in Medicine, 2021 - frontiersin.org
There are limited epidemiologic studies describing the global burden and geographic
heterogeneity of interstitial lung disease (ILD) subtypes. We found that among seventeen …