Metabolomics is based on cutting-edge analytical methods that provide a “snapshot” of all the detectable metabolites, small molecules generally weighing under 1200 Da, present in …
Nuclear magnetic resonance (NMR) spectroscopy is an important analytical technique in metabolomics. Because it provides atomic-level detail of small molecules, NMR is …
Y Wei, P Jasbi, X Shi, C Turner, J Hrovat… - Journal of proteome …, 2021 - ACS Publications
Breast cancer (BC) is a common cause of morbidity and mortality, particularly in women. Moreover, the discovery of diagnostic biomarkers for early BC remains a challenging task …
R Gao, C Wu, Y Zhu, C Kong, Y Zhu, Y Gao, X Zhang… - Gastroenterology, 2022 - Elsevier
Background & Aims Studies have reported abnormal gut microbiota or circulating metabolome associated with colorectal cancer (CRC), but it remains a challenge to capture …
NMR spectroscopy, one of the two major analytical platforms utilized in the metabolomics field, has witnessed a large number of advances in fundamental studies, methods …
J Zhang, Y Xiong, S Min - Analytica chimica acta, 2019 - Elsevier
Feature selection can greatly enhance the performance of a learning algorithm when dealing with a high dimensional data set. The filter method and the wrapper method are the …
NMR spectroscopy is an essential analytical technique in metabolomics and fluxomics workflows, owing to its high structural elucidation capabilities combined with its intrinsic …
A Au - Advances in clinical chemistry, 2018 - Elsevier
Ischemic stroke is a sudden loss of brain function due to the reduction of blood flow. Brain tissues cease to function with subsequent activation of the ischemic cascade. Metabolomics …
H Pang, W Jia, Z Hu - Clinical Pharmacology & Therapeutics, 2019 - Wiley Online Library
Metabolic disturbances have been associated with many human diseases, including cancer, diabetes, and cardiovascular disease. Metabolomics, a rapidly growing member of the …