Pharmacological inhibition of KDM5A for cancer treatment

GJ Yang, J Wu, L Miao, MH Zhu, QJ Zhou, XJ Lu… - European Journal of …, 2021 - Elsevier
Lysine-specific demethylase 5A (KDM5A, also named RBP2 or JARID1A) is a demethylase
that can remove methyl groups from histones H3K4me1/2/3. It is aberrantly expressed in …

Complex gastroschisis: a new indication for fetal surgery?

L Joyeux, MA Belfort, P De Coppi… - … in Obstetrics & …, 2021 - Wiley Online Library
Gastroschisis (GS) is a congenital abdominal wall defect, in which the bowel eviscerates
from the abdominal cavity. It is a non‐lethal isolated anomaly and its pathogenesis is …

[HTML][HTML] New clues to understand gastroschisis. Embryology, pathogenesis and epidemiology

L Chuaire Noack - Colombia Médica, 2021 - scielo.org.co
Abstract gastroschisis is a congenital structural defect of the abdominal wall, most often to
the right of the umbilicus, through which the abdominal viscera protrude. Its developmental …

MYBPC2 and MYL1 as significant gene markers for Rhabdomyosarcoma

Z Chen, X Li, P Guo, D Wang - Technology in Cancer …, 2021 - journals.sagepub.com
Background: Rhabdomyosarcoma is the most common soft tissue tumor in children.
Rhabdomyosarcoma commonly results in pain and bleeding caused by tumor compression …

Network protein interaction in Parkinson's disease and periodontitis interplay: a preliminary bioinformatic analysis

J Botelho, P Mascarenhas, JJ Mendes, V Machado - Genes, 2020 - mdpi.com
Recent studies supported a clinical association between Parkinson's disease (PD) and
periodontitis. Hence, investigating possible interactions between proteins associated to …

[HTML][HTML] Genetics and Genomics of Gastroschisis, Elucidating a Potential Genetic Etiology for the Most Common Abdominal Defect: A Systematic Review

JP Marquart, Q Nie, T Gonzalez, AC Jelin… - Journal of …, 2024 - mdpi.com
(1) Background: The exact etiology for gastroschisis, the most common abdominal defect, is
yet to be known, despite the rising prevalence of this condition. The leading theory suggests …

Whole exome sequencing identifies multiple novel candidate genes in familial gastroschisis

VM Salinas‐Torres, HL Gallardo‐Blanco… - … Genetics & Genomic …, 2020 - Wiley Online Library
Background Genetic association studies for gastroschisis have highlighted several
candidate variants. However, genetic basis in gastroschisis from noninvestigated heritable …

[HTML][HTML] Gastroschisis associated changes in the placental transcriptome

M Jongen, I Reddin, S Cave, L Cashmore, J Pond… - Placenta, 2024 - Elsevier
The congenital condition gastroschisis is associated with delayed villous development and
placental malperfusion, suggesting placental involvement. This study uses RNA sequencing …

Gastroschisis: embriology, pathogenesis, risk factors, prognosis, and ultrasonographic markers for adverse neonatal outcomes

TD Muniz, LC Rolo, E Araujo Júnior - Journal of Ultrasound, 2024 - Springer
Gastroschisis is the most common congenital defect of the abdominal wall, typically located
to the right of the umbilical cord, through which the intestinal loops and viscera exit without …

Prevalence rates study of selected isolated non‐Mendelian congenital anomalies in the Hutterite population of Alberta, 1980–2016

RB Lowry, T Bedard, S Crawford… - American Journal of …, 2020 - Wiley Online Library
A study of the prevalence rates for selected isolated non‐Mendelian congenital anomalies in
the Hutterite Brethren of Alberta, Canada was undertaken to further examine longitudinal …