The ongoing search for biodegradable and biocompatible microneedles (MNs) that are
strong enough to penetrate skin barriers, easy to prepare, and can be translated for clinical …

Insulin resistance (IR) has become a common health issue in medical practice. There are no
detailed data on IR prevalence, but it is an increasing problem due to its close association …

Acanthosis nigricans (AN) has been reported in relation to insulin resistance (IR). We aim to
review AN through an endocrine and metabolic perspective focusing on IR in association …

Due to its anti-hyperglycemic effect, metformin is the first-line medication for the treatment of
type 2 diabetes, particularly in people who are obese. However, metformin is a drug with a …

Background: Early recognition of acanthosis nigricans is important because acanthosis
nigricans can be a cutaneous manifestation of a variety of systemic disorders and, rarely, as …

Objective Little is known about specific cutaneous findings in children and adolescents with
overweight and obesity. This study assessed the association of skin signs with pivotal …

Cutaneous manifestations affect most patients with diabetes mellitus, clinically presenting
with numerous dermatologic diseases from xerosis to diabetic foot ulcers (DFUs). Skin …

Acanthosis nigricans (AN) is associated with obesity and type 2 diabetes, where insulin
resistance (IR) is considered a predisposing factor. IR can also affect patients with type 1 …

Background Acanthosis nigricans (AN) is a common chronic skin disorder clinically presents
by velvety hyperpigmented lesions mainly at the flexural areas. Fractional photothermolysis …

Objective To explore insulin secretion patterns, β-cell function, and serum prolactin (PRL)
concentrations in Chinese morbidly obese patients with Acanthosis nigricans (AN) and their …