[HTML][HTML] Cyclodextrin–drug inclusion complexes: In vivo and in vitro approaches

SB Carneiro, FI Costa Duarte, L Heimfarth… - International journal of …, 2019 - mdpi.com
This review aims to provide a critical review of the biological performance of natural and
synthetic substances complexed with cyclodextrins, highlighting:(i) inclusion complexes with …

[HTML][HTML] Cyclodextrin multicomponent complexes: Pharmaceutical applications

V Aiassa, C Garnero, MR Longhi, A Zoppi - Pharmaceutics, 2021 - mdpi.com
Cyclodextrins (CDs) are naturally available water-soluble cyclic oligosaccharides widely
used as carriers in the pharmaceutical industry for their ability to modulate several properties …

In vitro–in vivo evaluation of chitosan-PLGA nanoparticles for potentiated gastric retention and anti-ulcer activity of diosmin

WE Abd El Hady, EA Mohamed… - International journal …, 2019 - Taylor & Francis
Background Diosmin showed poor water solubility and low bioavailability. Poly (d, l-lactide-
co-glycolide)(PLGA) nanoparticles were successfully used to improve the drugs solubility …

Self-assembly of cyclodextrins and their complexes in aqueous solutions

A Ryzhakov, T Do Thi, J Stappaerts, L Bertoletti… - Journal of …, 2016 - Elsevier
Cyclodextrins (CDs) are enabling pharmaceutical excipients that can be found in numerous
pharmaceutical products worldwide. Because of their favorable toxicologic profiles, CDs are …

Development and evaluation of PLGA polymer based nanoparticles of quercetin

MK Anwer, MA Al-Mansoor, S Jamil… - International journal of …, 2016 - Elsevier
Quercetin is the most abundant antioxidant found in the human diet. Low aqueous solubility
of quercetin limits its bioavailability and hence therapeutic effects. Therefore, the aim of the …

[HTML][HTML] Diosmin is neuroprotective in a rat model of scopolamine-induced cognitive impairment

S Shabani, MA Mirshekar - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Objective Scopolamine, a muscarinic cholinergic receptor antagonist, is used as a standard
pharmaceutical model for inducing cognitive impairment in animals. Several cognitive …

Enhancing the water-solubility of curcuminoids-rich extract using a ternary inclusion complex system: Preparation, characterization, and anti-cancer activity

L Lateh, N Kaewnopparat, S Yuenyongsawad… - Food Chemistry, 2022 - Elsevier
Curcuminoids are known to exert diverse pharmacological effects and used in some
pharmaceutical formulations. This study describes the preparation, characterization, and …

[HTML][HTML] Preparation and evaluation of diosmin-loaded diphenylcarbonate-cross-linked cyclodextrin nanosponges for breast cancer therapy

MK Anwer, MM Ahmed, MF Aldawsari, M Iqbal… - Pharmaceuticals, 2022 - mdpi.com
In the current study, diosmin (DSM)-loaded beta-cyclodextrin (β-CD)-based nanosponges
(NSPs) using diphenylcarbonate (DPC) as a cross-linker were prepared. Four different DSM …

Preparation, evaluation and pharmacokinetic studies of spray dried PLGA polymeric submicron particles of simvastatin for the effective treatment of breast cancer

N Anzar, MA Mirza, K Anwer, T Khuroo… - Journal of molecular …, 2018 - Elsevier
In the current study, simvastatin-loaded PLGA submicron particles (SIM SP) were prepared
by the spray drying method. Different parameters of the nanospray drying method, such as …

[HTML][HTML] Diosmin-loaded nanoemulsion-based gel formulation: Development, optimization, wound healing and anti-inflammatory studies

MK Anwer, MF Aldawsari, M Iqbal, BK Almutairy… - Gels, 2023 - mdpi.com
The wound-healing process is complex and prone to interruption or failure, which can result
in the development of chronic wounds that never heal. This can be overcome by seeking …