Dementia affects all domains of cognition. The relentless progression of the disease after
diagnosis is associated with a 98% incidence of neuropsychiatric symptoms (NPS) at some …

Background For community-dwelling older persons with dementia, the presence of
multimorbidity can create complex clinical challenges for both individuals and their …

Despite efforts to raise awareness and develop guidelines for care of individuals with
dementia, reports of poor detection and inadequate management persist. This has led to a …

Background: There is limited evidence regarding the association between potentially
inappropriate medications (PIM) and mortality in older people with cognitive impairment …

Ainsley Moore MD MSc CCFP Christopher Frank MD CCFP (COE) FCFP Dementia is a
neurodegenerative condition affecting many areas of life at the same time. It is often …

Few studies have evaluated the association between anticholinergic burden and treatment
modification after starting a cholinesterase inhibitor in clinical practice. We aimed to evaluate …

Background Drugs with anticholinergic properties are considered potentially inappropriate
in patients with cognitive impairment because harms—including delirium, falls, and fractures …

Objectives To determine the prevalence of and resident characteristics associated with the
prescription of medications of questionable benefit (MQB s) near the end of life in older …

Background Medications with potent anticholinergic properties have well-documented
adverse effects. A high cumulative anticholinergic burden may arise from the concurrent use …

Background The aim of this study was to examine the risk of fall with the surrogate outcome
of the Aachen Falls Prevention Scale and to assess the clinical pharmacist interventions in …