Perspectives of aminoacylases in biocatalytic synthesis of N-acyl-amino acids surfactants

G Haeger, J Wirges, J Bongaerts, U Schörken… - Applied Microbiology …, 2024 - Springer
Many industrial processes are performed using harmful chemicals. The current technical
synthesis of N-acyl-amino acids relies on acyl chlorides, which are typically obtained from …

Bioinformatic mapping of a more precise Aspergillus niger degradome

Z Dong, S Yang, BH Lee - Scientific reports, 2021 - nature.com
Aspergillus niger has the ability to produce a large variety of proteases, which are of
particular importance for protein digestion, intracellular protein turnover, cell signaling …

Efficient synthesis of L-phosphinothricin using a novel aminoacylase mined from Stenotrophomonas maltophilia

CH Cao, F Cheng, YP Xue, YG Zheng - Enzyme and microbial technology, 2020 - Elsevier
Abstract L-phosphinothricin (L-PPT) is a competitive and environmentally friendly herbicide.
To develop an efficient approach for synthesis of l-PPT, a kinetic resolution route with a …

Diagnostics for Zika virus on the horizon

SD Speer, TC Pierson - Science, 2016 - science.org
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that is related to other pathogens of
clinical importance, including yellow fever and dengue (DENV) viruses. Although once …

Discovery of an ʟ-amino acid ligase implicated in Staphylococcal sulfur amino acid metabolism

JL Pederick, AJ Horsfall, B Jovcevski, J Klose… - Journal of Biological …, 2022 - ASBMB
Enzymes involved in Staphylococcus aureus amino acid metabolism have recently gained
traction as promising targets for the development of new antibiotics, however, not all aspects …

[HTML][HTML] Structural and functional analysis of the key enzyme responsible for the degradation of ochratoxin A in the Alcaligenes genus

A Sánchez-Arroyo, L Plaza-Vinuesa… - International Journal of …, 2024 - Elsevier
The potential to degrade ochratoxin A (OTA), a highly poisonous mycotoxin, was
investigated in cultures from Alcaligenes-type strains. Genome sequence analyses from …

Whole Genome Sequencing and Comparative Genomics of Six Staphylococcus schleiferi and Staphylococcus coagulans Isolates

MA Abouelkhair, SA Kania - Genes, 2024 - mdpi.com
Staphylococcus schleiferi and Staphylococcus coagulans, closely related bacterial species
within the Staphylococcus genus, present a challenge in classification and diagnosis due to …

Improving the annotation of amino acid biosynthesis pathways: GapMind 2024

MN Price, AL Shiver, LA Day, MT Bejar, HP Lesea… - bioRxiv, 2024 - biorxiv.org
GapMind is an automated web-based tool for annotating amino acid biosynthesis pathways
in bacterial and archaeal genomes. We updated GapMind to include recently identified …

The quest to burn fat, effortlessly and safely

W Fan, R Evans - Science, 2016 - science.org
Treatment of obesity and obesity-associated diseases has been challenging, with the first
potential cure claimed in 1934 with the protonophore 2, 4-dinitrophenol (DNP). This …

Identificación y caracterización de enzimas bacterianas con capacidad para transformar ocratoxina A

A Sánchez Arroyo - 2024 - docta.ucm.es
La ocratoxina A (OTA) es una micotoxina de gran relevancia debido a su alta prevalencia y
toxicidad. Esta toxina aparece frecuentemente en numerosas materias primas y productos …