[HTML][HTML] Choosing membrane mimetics for NMR structural studies of transmembrane proteins

DE Warschawski, AA Arnold, M Beaugrand… - … et Biophysica Acta (BBA …, 2011 - Elsevier
The native environment of membrane proteins is complex and scientists have felt the need
to simplify it to reduce the number of varying parameters. However, experimental problems …

Residual dipolar couplings in structure determination of biomolecules

JH Prestegard, CM Bougault, AI Kishore - Chemical reviews, 2004 - ACS Publications
The use of residual dipolar couplings (RDCs) in the analysis of biomolecular structure and
dynamics has expanded rapidly since its potential as a source of structural information on …

[HTML][HTML] Direct observation and characterization of DMPC/DHPC aggregates under conditions relevant for biological solution NMR

L van Dam, G Karlsson, K Edwards - Biochimica et Biophysica Acta (BBA) …, 2004 - Elsevier
We have used cryo-transmission electron microscopy (cryo-TEM) for inspection of
aggregates formed by dimyristoylphosphatidylcholine (DMPC) and …

Bicelles as model membranes for solid‐and solution‐state NMR studies of membrane peptides and proteins

I Marcotte, M Auger - Concepts in Magnetic Resonance Part A …, 2005 - Wiley Online Library
Bicelles are an attractive membrane mimetic system because of their planar surface and
lipid composition, which resemble biological membranes. In addition, their orientation and …

When detergent meets bilayer: birth and coming of age of lipid bicelles

UHN Dürr, R Soong, A Ramamoorthy - Progress in nuclear magnetic …, 2013 - Elsevier
► Lipid bicelles have matured to full membership in the club of lipid phases.► Numerous
techniques have elucidated the character traits of bicelles.► Bicelles are exemplary citizens …

Reinvestigation by phosphorus NMR of lipid distribution in bicelles

MN Triba, DE Warschawski, PF Devaux - Biophysical journal, 2005 - cell.com
Mixtures of dimyristoyl-phosphatidylcholine (DMPC) and dihexanoyl-phosphatidylcholine
(DHPC) in water form disks also called bicelles and different bilayer organizations when the …

Bicelles and nanodiscs for biophysical chemistry

EJ Dufourc - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2021 - Elsevier
Membrane nanoobjects are very important tools to study biomembrane properties. Two
types are described herein: Bicelles and Nanodiscs. Bicelles are obtained by thorough …

[HTML][HTML] The cytochromes P450 and b5 and their reductases—promising targets for structural studies by advanced solid-state NMR spectroscopy

UHN Dürr, L Waskell, A Ramamoorthy - Biochimica et Biophysica Acta …, 2007 - Elsevier
Members of the cytochrome P450 (cyt P450) superfamily of enzymes oxidize a wide array of
endogenous and xenobiotic substances to prepare them for excretion. Most of the drugs in …

Comprehensive examination of mesophases formed by DMPC and DHPC mixtures

TA Harroun, M Koslowsky, MP Nieh, CF de Lannoy… - Langmuir, 2005 - ACS Publications
Mixtures of long-and short-chain phospholipids, specifically 14: 0 and 6: 0
phosphatidylcholines (DMPC and DHPC), have been used successfully in NMR studies as …

Bicelles: a natural 'molecular goniometer'for structural, dynamical and topological studies of molecules in membranes

A Diller, C Loudet, F Aussenac, G Raffard, S Fournier… - Biochimie, 2009 - Elsevier
Major biological processes occur at the biological membrane. One of the great challenges is
to understand the function of chemical or biological molecules inside the membrane; as well …