Melanization plays important roles in diverse physiological processes in insects including
wound healing, tanning of the cuticle and immunity. Upon infection, pattern recognition …

The multifaceted innate immune system of insects is capable of fighting infection by a variety
of pathogens including those causing human malaria. Malaria transmission by the …

INTRODUCTION Control of mosquito vectors has historically proven to be an effective
means of eliminating malaria. Human malaria is transmitted only by mosquitoes in the genus …

Mosquito immunity studies have focused mainly on characterizing immune effector
mechanisms elicited against parasites, bacteria and more recently, viruses. However, those …

Leucine-rich repeat–containing proteins are central to host defense in plants and animals.
We show that in the mosquito Anopheles gambiae, two such proteins that antagonize …

Arboviruses are transmitted by mosquitoes and other arthropods to humans and animals.
The risk associated with these viruses is increasing worldwide, including new emergence in …

The causative agent of malaria, Plasmodium, has to undergo complex developmental
transitions and survive attacks from the mosquito's innate immune system to achieve …

A causative agent of human malaria, Plasmodium falciparum, is transmitted by Anopheles
mosquitoes. The malaria parasite is under intensive attack from the mosquito's innate …

Plasmodium development within Anopheles mosquitoes is a vulnerable step in the parasite
transmission cycle, and targeting this step represents a promising strategy for malaria …

In the Americas, areas with a high risk of malaria transmission are mainly located in the
Amazon Forest, which extends across nine countries. One keystone step to understanding …