Chemistry, formation and occurrence of genotoxic heterocyclic amines identified in model systems and cooked foods

M Jägerstad, K Skog, P Arvidsson… - … und-Forschung A, 1998 - Springer
Some 20 years ago, Japanese scientists discovered a new group of highly mutagenic
compounds, classified as heterocyclic aromatic amines, from broiled and grilled meat and …

Formation of heterocyclic aromatic amines in model systems

M Murkovic - Journal of Chromatography B, 2004 - Elsevier
Heterocyclic aromatic amines (HAs) are mutagenic and carcinogenic substances that are
formed in significant amounts during heating of meat or fish at temperatures of at least 150° …

Well-done, grilled red meat increases the risk of colorectal adenomas

R Sinha, WH Chow, M Kulldorff, J Denobile, J Butler… - Cancer Research, 1999 - AACR
Red meat or meat-cooking methods such as frying and doneness level have been
associated with an increased risk of colorectal and other cancers. It is unclear whether it is …

Effects of smoking or baking procedures during sausage processing on the formation of heterocyclic amines measured using UPLC-MS/MS

D Yang, Z He, D Gao, F Qin, S Deng, P Wang, X Xu… - Food Chemistry, 2019 - Elsevier
We used an UPLC-MS/MS method to investigate the effects of smoking or baking on the
formation of heterocyclic amines (HAs) in sausage processing. We used principal …

Heterocyclic amines: chemistry and health

KW Cheng, F Chen, M Wang - Molecular Nutrition & Food …, 2006 - Wiley Online Library
Heterocyclic amines (HAs) occur at the ppb range in foods. Most of them demonstrate potent
mutagenicity in bacteria mutagenicity test, and some of them have been classified by the …

Relative exposure to β-carbolines norharman and harman from foods and tobacco smoke

T Herraiz* - Food additives and contaminants, 2004 - Taylor & Francis
Norharman and harman are two heterocyclic β-carboline (9 H-pyrido [3, 4-b] indole)
alkaloids with biological and potential toxicological activity that appear in foodstuffs and …

Effects of heating conditions and additives on the formation of heterocyclic amines with reference to amino-carbolines in a meat juice model system

K Skog, A Solyakov, M Jägerstad - Food Chemistry, 2000 - Elsevier
Common cooked meat and fish products contain heterocyclic amines. Lyophilised bovine
meat juice of known composition has been studied in a model system to increase …

Evaluation of the single cell gel electrophoresis assay with human hepatoma (Hep G2) cells

M Uhl, C Helma, S Knasmüller - Mutation Research/Genetic Toxicology and …, 2000 - Elsevier
Human Hep G2 cells have retained the activities of phase I and phase II enzymes which are
involved in the metabolism of environmental genotoxins. The present study describes the …

Exposure to heterocyclic aromatic amines from the consumption of cooked red meat and its effect on human cancer risk: a review

MS Alaejos, V González, AM Afonso - Food Additives and …, 2008 - Taylor & Francis
This review covers the bibliographic data from the last 10 years on the possible
carcinogenicity of heterocyclic aromatic amines (HAAs) in humans. Aspects such as red …

Adsorption of single-ringed N-and S-heterocyclic aromatics on carbon nanotubes

L Wang, D Zhu, L Duan, W Chen - Carbon, 2010 - Elsevier
Adsorption of single-ringed N-and S-heterocyclic aromatics on single-walled carbon
nanotubes (SWCNTs) was examined to explore the potential of using carbon nanotubes …