Should we evaluate and treat sperm DNA fragmentation?

A Agarwal, CL Cho, SC Esteves - Current Opinion in Obstetrics …, 2016 - journals.lww.com
Sperm DNA fragmentation tests provide clinically relevant information for natural conception
and artificial reproduction independent of those derived from conventional semen …

Fertility testing and ICSI sperm selection by hyaluronic acid binding: clinical and genetic aspects

G Huszar, A Jakab, D Sakkas, CC Ozenci… - Reproductive …, 2007 - Elsevier
The testis-expressed chaperone protein, HspA2 (previously creatine kinase M isoform) was
established as a measure of human sperm cellular maturity, function and fertility. The …

[HTML][HTML] “Physiologic ICSI”: hyaluronic acid (HA) favors selection of spermatozoa without DNA fragmentation and with normal nucleus, resulting in improvement of …

L Parmegiani, GE Cognigni, S Bernardi, E Troilo… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To evaluate the role of hyaluronic acid (HA) for sperm selection before
intracytoplasmic sperm injection (ICSI). DESIGN: Three prospective studies. SETTING …

[HTML][HTML] Intracytoplasmic sperm injection: a novel selection method for sperm with normal frequency of chromosomal aneuploidies

A Jakab, D Sakkas, E Delpiano, S Cayli, E Kovanci… - Fertility and sterility, 2005 - Elsevier
OBJECTIVE: To test a newly invented intracytoplasmic sperm injection (ICSI) sperm
selection method based on sperm hyaluronic acid (HA) binding. DESIGN: Comparison of …

Genetic aspects of monomorphic teratozoospermia: a review

M De Braekeleer, MH Nguyen, F Morel… - Journal of assisted …, 2015 - Springer
Teratozoospermia is characterized by the presence of spermatozoa with abnormal
morphology over 85% in sperm. When all the spermatozoa display a unique abnormality …

Intracytoplasmic morphologically selected sperm injection: a prospective randomized trial

M Antinori, E Licata, G Dani, F Cerusico… - Reproductive …, 2008 - Elsevier
The aim of this prospective randomized study was to assess the advantages of a new
modified intracytoplasmic sperm injection (ICSI) technique called intracytoplasmic …

Use of hyaluronan in the selection of sperm for intracytoplasmic sperm injection (ICSI): significant improvement in clinical outcomes—multicenter, double-blinded and …

KC Worrilow, S Eid, D Woodhouse, M Perloe… - Human …, 2013 - academic.oup.com
STUDY QUESTION Does the selection of sperm for ICSI based on their ability to bind to
hyaluronan improve the clinical pregnancy rates (CPR)(primary end-point), implantation (IR) …

[HTML][HTML] Fragmentation of DNA in morphologically normal human spermatozoa

C Avendaño, A Franchi, S Taylor, M Morshedi… - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To evaluate DNA fragmentation in spermatozoa with normal morphological
appearance. DESIGN: Prospective study. SETTING: Academic tertiary center. PATIENT (S) …

High-power microscopy for selecting spermatozoa for ICSI by physiological status

A Garolla, D Fortini, M Menegazzo, L De Toni… - Reproductive …, 2008 - Elsevier
Sperm selection for intracytoplasmic sperm injection (ICSI), based on standard morphology,
can fail to select normal cells, and actual methods to evaluate their physiological status do …

Efficiency of hyaluronic acid (HA) sperm selection

L Parmegiani, GE Cognigni, W Ciampaglia… - Journal of assisted …, 2010 - Springer
Abstract Purpose Hyaluronic Acid (HA) has a role as “physiologic selector” for spermatozoa
prior to intracytoplasmic sperm injection (ICSI). The objective of this study is to analyze the …