Moebius Syndrome: an updated review of literature

SA Monawwer, S Ali, R Naeem, SH Ali… - Child Neurology …, 2023 - journals.sagepub.com
Moebius Syndrome, is a rare, non-progressive congenital neuropathological syndrome
characterized primarily by the underdevelopment of the facial (CN VII) and abducens nerve …

Congenital cranial dysinnervation disorders: a concept in evolution

TM Bosley, KK Abu-Amero… - Current opinion in …, 2013 - journals.lww.com
The CCDD concept has focused attention on specific congenital disturbances of human
ocular motility and on the fact that these disorders are typically neurogenic in origin. The …

Moebius syndrome: clinical features, diagnosis, management and early intervention

O Picciolini, M Porro, E Cattaneo, S Castelletti… - Italian journal of …, 2016 - Springer
Background Moebius syndrome (MBS) is rare disease characterized by nonprogressive
congenital uni-or bi-lateral facial (ie VII cranial nerve) and abducens (ie VI cranial nerve) …

De novo mutations in PLXND1 and REV3L cause Möbius syndrome

L Tomas-Roca, A Tsaalbi-Shtylik, JG Jansen… - Nature …, 2015 - nature.com
Möbius syndrome (MBS) is a neurological disorder that is characterized by paralysis of the
facial nerves and variable other congenital anomalies. The aetiology of this syndrome has …

Diagnostic distinctions and genetic analysis of patients diagnosed with Moebius syndrome

S MacKinnon, DT Oystreck, C Andrews, WM Chan… - Ophthalmology, 2014 - Elsevier
Objective To improve diagnostic assessment in Moebius syndrome by (1) creating more
selective diagnostic subgroups and (2) conducting genetic evaluation in a large patient …

Characterization of ocular motor deficits in congenital facial weakness: Moebius and related syndromes

JC Rucker, BD Webb, T Frempong, H Gaspar… - Brain, 2014 - academic.oup.com
Congenital facial weakness is present in a heterogeneous group of conditions. Among them
is Moebius syndrome, which has been defined as a disorder with congenital, non …

The epidemiology of Moebius syndrome in Italy

A Carta, S Favilla, G Calzetti, MC Casalini… - Orphanet journal of rare …, 2021 - Springer
Abstract Background The epidemiology of Moebius syndrome (MBS) is difficult to assess. In
the present study, we investigated the epidemiology of MBS in a well-defined population …

A framework for the evaluation of patients with congenital facial weakness

BD Webb, I Manoli, EC Engle, EW Jabs - Orphanet journal of rare …, 2021 - Springer
There is a broad differential for patients presenting with congenital facial weakness, and
initial misdiagnosis unfortunately is common for this phenotypic presentation. Here we …

Genetics of Strabismus

MC Whitman, EC Engle - Albert and Jakobiec's Principles and Practice of …, 2022 - Springer
Many forms of both syndromic and nonsyndromic strabismus have an underlying genetic
basis. Many genetic syndromes, especially neurological syndromes, can include strabismus …

Síndrome de Moebius. Reporte de un caso clínico.

V Canalejo-Saavedra, R Sierra-García… - Revista Mexicana …, 2018 - search.ebscohost.com
Introducción: El síndrome de Moebius es una entidad clínica neurológica congénita
caracterizada por parálisis bilateral de dos pares craneales, el (VII) facial y (VI) oculomotor …